Reward & Addiction Self Administration Box The self-administration box is an entirely modular experimental enclosure designed to conduct a wide variety of different schedules for studying reward and addiction in laboratory animals. The chamber is assembled with black aluminum walls and a transparent front door. The chambers employ a stainlesssteel grid floor that allows waste to collect in a removable tray. All floor components (including the grid) are removable for systematic cleaning. Special modules are available for self-administration and selfstimulation procedures: lever or nose-spoke, food or drink dispensers, drug delivery system and stimuli (light, sound, shock, etc.). Each chamber is associated with a LinkBox which provides power to up to 8 (expandable to 16) selfadministration modules conferring to the chambers a full autonomy. Only one cable connects the LinkBox to the PC, this last for advanced protocol configuration and running. All self-administration boxes are associated with the potent and versatile Packwin software which allows configuring any kind of user-defined schedules (training, priming, fixed-ratio, progressive ratio, extinction, relapse, etc.) and providing relevant data in this context (number of pressing on active and inactive levers, number of injections received, pattern response graph, etc.). Packwin must be ordered separately. Reward & Addiction • Self Administration Box key features } Entirely modular box } Easily removable waste tray } Associated with Packwin software } Reduced number of cables } Neither PC interface nor PC cards are required parameters measured Ordering Information Order # 76-0151 76-0152 76-0153 76-0154 76-0156 76-0157 76-0566 76-0002 76-0592 Model Le1002 Le1005 Le100201 Le100501 LinKboX01 Le26 Le26m PacKwin Product modular operant chamber, mice (needs Shockable grid) modular operant chamber, rat (needs Shockable grid) mice Shockable grid rats Shockable grid Link & Power Supply for up to 8 chamber modules. rS-232 output Sound-Proof box Sound-Proof box, mice multipurpose behavior Software } Number of responses (lever pressing or nose-poke) } Response rate } Number of reinforcements received } Number of responses during drug injection & time-out } User-defined parameters capabilities } Cumulative curve graph } Reponse pattern graph components included } Experimental chamber } Instruction manual } Cables and connectors } 2 year warranty options PacKwincS customized experimental module, needs experimental modules contact representative for optional modules and accessories. } Linkbox (power connection box) } Wide range of modules } Sound-attenuating box } Packwin software note RefeRences Bodetto SP et al. (2014) Differential regulation of MeCP2 and PP1 in passive or voluntary administration of cocaine or food. Int J Neuropsychopharmacol. 2014 Dec;17(12):2031-44. www.panlab.com • www.coulbourn.com 85