Analgesia Plethysmometer for Evaluating Paw Volume (continued) Specifications control Unit Dimensions (W x D x H) stimulation Unit Dimensions (W x D x H) Power supply starting Resolution Material composition 280 x 280 x 110 mm (11 x 11 x 4 in) 230 x 220 x 300 mm (9 x 9 x 12 in) 220/110 Vac, 50/60 Hz by panel key or pedal switch 3 digits, 0.01 steps clear methacrylate (cell), stainless steel (stand), platinum (electrode) ce compliant RefeRences Silva JC et al. (2015) Antinociceptive and anti-inflammatory activities of the ethanolic extract of Annona vepretorum Mart. (Annonaceae) in rodents. BMC Complement Altern Med. 2015 Jun 24;15:197. (Brazil) Coura CO et al. (2015) Mechanisms involved in the anti-inflammatory action of a polysulfated fraction from Gracilaria cornea in rats. PLoS One. 2015 Mar 25;10(3):e0119319. (rat) Illuri R et al. (2015) Anti-Inflammatory Activity of Polysaccharide Fraction of Curcuma longa Extract (NR-INF-02). Antiinflamm Antiallergy Agents Med Chem. 2015;14(1):53-62. (rat) Ravalji M et al. (2015) Investigation of centrally and peripherally acting analgesic and anti inflammatory activity of biological immune response modulator (an Amazonian plant extract) in animal models of pain and inflammation. Int J Basic Clin Pharmacol. 2015; 4(2): 342-348. (mouse) Batista JA et al. (2014) Polysaccharide isolated from Agardhiella ramosissima: chemical structure and anti-inflammation activity. Carbohydr Polym. 2014 Jan;99:59-67. Analgesia • Plethysmometer for Evaluating Paw Volume certifications Ordering Information Order # 76-0220 Model Le7500 Product Digital water Plethysmometer (electrodes, cell, calibrator and SeDacom software supplied separately) 1 ml cell with electrode and 1 ml calibrator 3 ml cell with electrode and 3 ml calibrator 5 ml cell with electrode and 5 ml calibrator Platinum electrode 1 ml calibrator for Plethysmometer 3 ml calibrator for Plethysmometer 5 ml calibrator for Plethysmometer Belkouch M et al. (2014) Functional up-regulation of Nav1.8 sodium channel in A⁸ afferent fibers subjected to chronic peripheral inflammation. J Neuroinflammation. 2014 Mar 7;11:45. (rat) Carneiro JG et al. (2014) Peripheral Antinociception and Anti-Inflammatory Effects of Sulphated Polysaccharides from the Alga Caulerpa mexicana. Basic Clin Pharmacol Toxicol. 2014 Mar 27. [Epub ahead of print] (mouse) Chaudhary H et al. (2014) A novel nano-carrier transdermal gel against inflammation. Int J Pharm. 2014 Apr 25;465(1-2):175-86. Damasceno SR et al. (2014) Carvacryl acetate, a derivative of carvacrol, reduces nociceptive and inflammatory response in mice. Life Sci. 2014 Jan 14;94(1):58-66. (mouse) Dias JM et al. (2014) Gabapentin, a Synthetic Analogue of Gamma Aminobutyric Acid, Reverses Systemic Acute Inflammation and Oxidative Stress in Mice. Inflammation. 2014 May 7. [Epub ahead of print] (mouse) Jeengar MK et al. (2014) Improvement of Bioavailability and Anti-Inflammatory Potential of Curcumin in Combination with Emu Oil. Inflammation. 2014 Jul 16. [Epub ahead of print] (rat) Lopes LC et al. (2014) Pharmacological characterization of Solanum cernuum Vell.: 31-norcycloartanones with analgesic and anti-inflammatory properties. Inflammopharmacology. 2014 Jun;22(3):179-85. ( Pereira JG et al. (2014) Polysaccharides isolated from Digenea simplex inhibit inflammatory and nociceptive responses. Carbohydr Polym. 2014 Aug 8;108:17-25. (mouse) Queiroz JC et al. (2014) Evaluation of the Anti-Inflammatory and Antinociceptive Effects of the Essential Oil from Leaves of Xylopia laevigata in Experimental Models. ScientificWorldJournal. 2014;2014:816450. (mouse) Rizzo LY et al. (2014) In vitro, in vivo and in silico analysis of the anticancer and estrogenlike activity of guava leaf extracts. Curr Med Chem. 2014;21(20):2322-30. (mouse) Sakat SS et al. (2014) Release-active dilutions of diclofenac enhance anti-inflammatory effect of diclofenac in carrageenan-induced rat paw edema model. Inflammation. 2014 Feb;37(1):1-9. (rat) Al.Fararjeh MA et al. (2013) Evaluation of Immunomodulatory Effects of Antiepileptic Drug Phenytoin. Jordan Journal of Biological Sciences. Volume 6, Number 4, December, Pages 328 – 333. (mouse) Muhammad N et al. (2013) Analgesic and anti-inflammatory profile of n-hexane fraction of viola betonicifolia. Tropical Journal of Pharmaceutical Research. Vol 11, No 6. (mouse Nalbantsoy A et al. (2013) Viper venom induced inflammation with Montivipera xanthina (Gray, 1849) and the anti-snake venom activities of Artemisia absinthium L. in rat. Toxicon. 2013 Apr;65:34-40. (rat) Pinto NV et al. (2013) Inflammatory and hyperalgesic effects of oxidized multi-walled carbon nanotubes in rats. J Nanosci Nanotechnol. 2013 Aug;13(8):5276-82. Sakat SS et al. (2013) Release-Active Dilutions of Diclofenac Enhance Anti-inflammatory Effect of Diclofenac in Carrageenan-Induced Rat Paw Edema Model. Inflammation. 2013 Sep 5. In Press (rat) Ullah N et al. (2013) Bioisosteric synthesis of nitrogen containing derivatives of salicyl alcohol, their in vivo pharmacological studies with molecular modelling. Medicinal Chemistry Research, October 2013, Volume 22, Issue 10, pp 4677-4684 Vishwakarma S et al. (2013) Tubastatin, a selective histone deacetylase 6 inhibitor shows anti-inflammatory and anti-rheumatic effects. Int Immunopharmacol. 2013 May;16(1):72-8. (mouse) 76-0221 76-0223 76-0222 Options 76-0224 76-0225 76-0226 76-0436 76-0406 76-0608 Le7504 Le7503 Le7505 Le7506 Le75301 Le75303 Le75305 SeDacomV2.0 SeDacom V2.0 conrS232uSb rS232/uSb adapter 50 www.coulbourn.com • www.panlab.com