Sensory Motor & Coordination Grip Strength Meter for Evaluation of Muscular Strength The grip strength meter allows the study of neuromuscular functions in rodents by determining the maximum force displayed by an animal. This test is included in the Functional Observational Battery (FOB) to screen for neurobehavioral toxicity. In this context, changes in grip strength are interpreted as evidence of motor neurotoxicity. The grip strength meter is positioned horizontally and the subjects are held by the tail and lowered towards the apparatus. The animals are allowed to grasp the metal grid or T-bar and are then pulled backwards in the horizontal plane. The force applied to the grid or to the bar just before it loses grip is recorded as the peak tension. This force can be measured in kilograms, grams, pounds or Newtons. Data output is carried out through RS-232, printer, or chart recorder. Depending on the grid type used, grip strength can be measured from the front or hind paws. Bar for Rat Bar for Mouse (for front or rear paws) Sensory Motor & Coordination • Grip Strength Meter for Evaluation of Muscular Strength Grid for Mouse Grid for Rats (for four paws) (for front paws & four paws) Specifications Dimensions of single system (W x D x H) 400 x 180 x 200 mm (15.7 x 7 x 7.9 in) Dimensions of 2 Grid system (W x D x H) 750 x 180 x 200 mm (29.5 x 7 x 7.9 in) sensor capacity sampling speed Measurement Range Resolution Accuracy Material composition Power supply 0-2 kg (20n) 1000 Hz 0 to 2000 grams 0.1 gram 0.1 % of full scale Stainless steel (grid) 110/220 Vac (for front or rear paws) key features } Stand alone system, PC optional, not required } Fits rats or mice with a simple change of grip accessories } Multi-units display: kgs, grams, lbs, Newtons } New and unique internal computations allow direct reading of average value, standard deviation and variability for up to 100 subject animals parameters measured Ordering Information Order # 76-0483 Options 76-0484 76-0485 76-0479 76-0480 76-0481 76-0482 RefeRences Menzies FM et al. (2015) Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity. Cell Death Differ. 2015 Mar;22(3):433-44. (mice, UK, USA) } Maximum force developed by the front and hind paws components included Model biogS3 Product grip Strength test complete with 1 accessory, 110 or 220 Volts Data acquisition rSic Software windows® XP (Dongle and cD) rS-232 cable bar for rats (front Paws) bar for mice (front or rear Paws) grid for rats (front or four Paws) grid for mice (front & four paws) } Display unit with RS-232 connection for PC } Metal stand } One accessory (one or two grids/bars) } Instruction manual } 1 year warranty options biorSic bioagrS232 biogriPbr biogriPbS biogriPgr biogriPgS } RS-232 cable } RSIC software } Additional grid/bar www.panlab.com • www.coulbourn.com 31