Analgesia Thermal Gradient Test Independent Thermal Test Demonstrates Place Preference and Temperature Comfort Thresholds for Rodents! As described by Moqrich et al. 2005, our Thermal Gradient Test monitors thermal nociception completely independently on freely moving rodents. A continuous temperature gradient (5 to 55°C) is established over a 120 cm long base plate on which the animal is free to walk. After an exploration period of acclimation, the animal clearly shows a distinct zone preference. Our model is an automated system which maintains the temperature gradient stable over the surface and over time. The accompanying software, coupled to a video camera, displays for each animal the time spent in each temperature zone, together with overall distance travelled. The encrypted data and video images are recorded synchronously in real time during the experiments and the user is able to replay the files to analyze or review. Analgesia • Thermal Gradient Test Specifications Overall Dimensions (L x W x H): 2 mice/1 rat 139 x 30 x 40 cm (54.7 x 11.8 x 15.6 in) 25 kg (33.1 lbs) 110/220 Vac 2 mice/1 rat 125 x 10 x 15 cm (49.2 x 3.9 x 5.9 in) 5 to 55° c at plate surface 20 to 25°, 50% rH at environment 1°c surface, over time aluminum alloy gray PPc transparent PPc Overall Weight: 2 mice/1 rat Power supply number of Lanes Lane Dimensions: 2 mice/1 rat Temperature Range Temperature stability system Material: Base Plate Walls Top cover key features } Continuous thermal gradient established over a 120 cm long base plate } Monitor 2 mice or 1 rat parameters measured } Up to 20 temperature zones measured per animal } Time spent in each temperatures zone } Temperature of zone over time period } Overall distance travelled components included } Two thermal units } Controllers } Cage } Base plate Ordering Information Order # 76-0477 Model biograDient Product thermal gradient test, 2 mice/1 rat 44 www.coulbourn.com • www.panlab.com