Analgesia Dynamic Weight Bearing Test for Measuring the Postural Equilibrium on Freely Moving Rodents Analgesia the averaged values are encrypted and recorded on a PC through a USB link along with the sampling rate of 10 Hz. Analysis and replay can be performed on-site or remotely. Replaying the experiment with the recorded video file allows the operator to further complement the posture and behavior of the animal, enhancing the interest of the test. During this time, the user can check and secure each limb recognition. The weight distribution of the animal, per limb, is shown in the result window for each time period with the mean and variation coefficient. All data is presented in the Excel file. key features } Measure independently the weight bore by each limb of a freely moving animal } Data capture allows for analysis and replay to be performed for user validation of data } Accuracy and resolution insured by an initial calibration } Minimal stress design minimizes habituation period for higher throughput parameters measured } Weight for each paw (g and % total animal weight) } Weight for grouped front and rear paws (g and %total animal weight) } Left/Right and Front/Rear weight ratio } Surface for each paw (mm²) } Surface for grouped front and rear paws (mm²) } Variability (standard deviation/mean) for each parameter } Parameters are given for each posture and as a mean for the whole experiment } Duration of different postures (4 paws, rearing…) over the whole experiment (s) } Total time spent on each paw over the whole experiment (s) } Raw data is encrypted (GLP) and recorded with a sampling rate of 10 Hz including synchronized video recording components included } Animal cage } One sensor } USB interface } Webcam } Software • Dynamic Weight Bearing Test Specifications Overall Dimensions (L x W x H cm): Mouse Rat Overall Weight: Mouse Rat Power supply Mouse Rat sensor Accuracy: Mouse Rat sensor Resolution: Mouse Rat sensor Range: Mouse Rat cage Material: floor Walls computer Requirements gray PPc transparent PPc windows 7, core i3 or i5 processor with a minimum of 3 go of ram 15 to 50 g (0.53 to 1.76 oz) 150 to 500 g (5.29 to 17.63 oz) 0.2 g (0.007 oz) 0.8 g (0.028 oz) 1 g (0.035 oz) 1 g (0.035 oz) 1 kg (2.2 lbs) 2.5 kg (5.5 lbs) from Pc uSb port 11.5 x 11.5 x 22 cm (4.5 x 4.5 x 8.6 in) 22 x 22 x 30 cm (8.6 x 8.6 x 12 in) 17 x 17 x 22 cm (6.7 x 6.7 x 8.6 in) 30 x 30 x 35 cm (11.8 x 11.8 x 14 in) Animal cage Internal Dimensions: Ordering Information Order # 76-0474 76-0728 76-0718 Model bio-Dwb-r Product Dynamic weight bearing test, rat bio-Dwb-m Dynamic weight bearing test, mouse bioDwbDuaL Dynamic weight bearing test, with camera, two sensor pads, interface and software (Pc not included) – dual for rats and mice bioDwbmc bioDwbrc replacement pad for mice replacement pad for rat Newly developed, our Dynamic Weight Bearing Test, features a floor instrumented cage. This allows independent measurement of the weight bore by each limb for the freely moving animal. This system accuracy and resolution are ensured via a metrological calibration performed prior to the data capture. During the data capture, the raw data for each paw are synchronized with the images from a video camera and 76-0493 76-0719 www.panlab.com • www.coulbourn.com 51