Learning Memory & Attention Startle & Fear Combined System Learning Memory & Attention • Startle & Fear Combined System key features options } Combined system for startle/freezing } Combined system for mice/rats for fear conditioning paradigms } Weight transducer sensitivity optimized } Different spacial context configurations available } Accurate and traceable data } USB connection, one cable links all! parameters measured } Shock Generator } Air Puff Unit } Packwin V2.0 Software with: • Freezing Module • Startle Module } Time of experiment at which each inactivity event has occurred (FREEZING) The StartFear Combined system is a polyvalent system for conducting both fear conditioning and startle reflex experiments in one same enclosure, regardless if the animal is a rat or a mouse (from 15g to 300 g). Basically, the StartFear system allows recording and analysis of the signal generated by the animal movement through a high sensitivity Weight Transducer system. The analogical signal is transmitted to the FREEZING and STARTLE software modules through the load cell unit for recording purposes and posterior analysis in terms of activity/ immobility (FREEZING) or startle response characterization (STARTLE). An additional interface associated with corresponding hardware allows controlling the stimuli (light, sounds, shock, air puff) from the STARTLE and FREEZING modules of the PACKWIN software (PACKWINCSST and PACKWINCSFR, respectively). The StartFear cage is made with black methacrylate walls and a transparent front door. In fear conditioning experiment, the walls, cover and floor can be of different materials or colors. Moreover, a transparent cylinder can be placed into the experimental chamber in order to modify the contextual spatial perception of the subject during the test phase. (continued on next page) } Duration of each inactivity event (FREEZING) } Summary table of the total amount of freezing in each state of the experiment (FREEZING) } Number and duration of freezing episodes in each user-defined intervals of time (FREEZING) } Maximum amplitude of startle response (STARTLE) } Latency until the maximum amplitude of startle response (STARTLE) } Duration of the startle response (STARTLE) } Latency until the beginning of the startle response (STARTLE) } Average of the startle response (STARTLE) } Mean startle values for each trial type (STARTLE) components included } Experimental chamber } Sound proof box } Load cell amplifier } Station interface } Instruction manual } 2 year warranty www.panlab.com • www.coulbourn.com 69