Analgesia Plethysmometer for Evaluating Paw Volume Digital Water Plethysmometer The Digital Water Plethysmometer is designed to provide a highly useful tool in the measurement of small volume changes. This test is typically used to follow the evolution of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or antioedema properties of pharmacological substances. The volume transducer is formed by two Perspex tubes interconnected and filled with a conductive solution and a platinum electrode for each chamber. All the system is supported by a stand (included) that can be placed over the control unit. The water displacement produced by the immersion of the animal paw in the measuring tube is reflected into the second tube, inducing a change in the conductance between the two platinum electrodes. The Plethysmometer Control Unit detects the conductance changes and generates an output signal to the digital display indicating the volume displacement measured (0.01 ml resolution). The current value remains in the digital display until a new trial starts. The Control Unit is automatically zeroed between successive readings, thus making intermediate adjustments unnecessary. The system includes as standard a volume transducer with its related calibrator and a 100 ml solution. A remote footswitch allows rapid hands-free experiments and can be used to set control the end point of the measurement. SEDACOM software, ordered separately, can be used to automatically record the results on a PC. (continued on next page) Analgesia • Plethysmometer for Evaluating Paw Volume key features } Computer interface } “Check solution” status button } Conductive solution is easy to prepare or source } Footswitch control } Automatic zero adjustment parameters measured } Paw volume (ml) components included } Control Unit with RS-232 communication port to PC } Pedal switch } Stimulation unit } Instruction manual } Cables and connectors } Set of spare fuses } Certificate of calibration } 2 year warranty options } 1 ml, 3 ml or 5 ml cell with electrode } 1 ml, 3 ml or 5 ml volume gauge } SEDACOM software } RS-232/USB Adapter www.panlab.com • www.coulbourn.com 49