Anxiety & Depression Vogel Test The Vogel test has become a standard for fast screening the potential anxiolytic properties of drugs. In this procedure the drinking behavior is punished by mild shocks which leads to a significant reduction of water consumption in deprived animals. Drinking responses are then reestablished using drugs with anxiolytic properties. Our Vogel test consists of a standard home cage with a grid floor. An electronic unit associated with a special nipple ensures the detection and counting of the licks reflecting the animal drinking behavior. Using this exclusive nipple design, any casual and non-specific contacts of the animal with the nipple will not be considered as a drinking response. Our multi-cage configuration allows the Vogel test to be performed on up to 32 cages. The cages are associated with our LinkBox Interface (1 for each 8 cages) ensuring the functional interaction between the lick sensor system, the LE10025 Shock generator (1 per cage) and the Packwin software for advanced protocol configuration and data acquisition. The interconnection among the cages and the computer is carry out by a RS-232 serial communication. key features Anxiety & Depression • Vogel Test } Allows Vogel experiments directly in the animal’s home cage Specifications Le3208 Le10025 internal memory for up to 99 trials Shocker intensity: from 0.1 to 2 ma; duration: from 0.1 to 10 sec } Exclusive nipple system to exclude non-specific contacts single computer } Up to 32 cages can be associated with a parameters measured Ordering Information Order # 76-0316 76-0621 76-0334 76-0156 76-0002 76-0594 76-0592 Options 76-0319 76-0320 Le8624 Le8626 Vogel test nipple Plus bottle electric contacts for nozzle and grid Model Le862 Le865 Le10025 LinKboX01 PacKwin2.0 PacKwinVt PacKwincS Product Vogel test Set for mice or rats <300g (excluding control unit) Vogel test Set for Large rats (excluding control unit) Shock generator with Scrambler (1 per cage) Plus Lick Detector Link box interface for up to 8 cages Packwin 2.0 Packwin Vogel test module customized module } Total number of licks per trial } Total number of shocks received per trial components included } LinkBox interface for up to 8 cages } Cage with lick detector } Bottle with special nipple } Cables and connectors } Instruction manual } 2 year warranty options } Packwin Software to control up to 32 cages } LE10025 Shocker unit with scrambler (0-2 mA output) plus lick detector 78 www.coulbourn.com • www.panlab.com