NanoCool
TM
Injector
Harvard Apparatus
phone
508.893.8999
toll free U.S.
800.272.2775
fax
508.429.5732
www.harvardapparatus.com
SYRINGE PUMPS
NanoCool
TM
Injector
29
Order #
Product
PC5 88-1050
NanoCool
TM
Injector
KEY FEATURES
18ºC for optimal cell viability on any delivery syringe
and Eppendorf
20% Increase in Survivability, 76% Lower O
2
Consumption
Rate at 18ºC vs. 37ºC
Flow ramping to reduce injection site blowback
Programmed methods for automatic recall of entire
cell delivery system. Up to 100 methods stored for recall
2 year warranty
High accuracy delivery between 3.66 pl/min to 1.91 ml/min
Preprogrammed bolus injection mode,
just specify injection size and time of dispense
Footswitch activation keeps hands free
NanoCool
TM
Cell Delivery System
When injecting stem cells viability of cells can be a major issue. The
injection system and sample vortex holder are held at 18ºC. The cell
delivery is totally integrated in it operation through the NanoCool's
microprocessor system: power, temperature injection volumes and
flow ramping are all controlled by the NanoCool's program. Keeping
the cells at 18ºC instead of 37ºC reduces O
2
consumption of cells by
an average of 76%. The chart to the right shows the different organ
utilization curves.
NanoCool
TM
Injector
Specifications
ACCURACY
±0.5%
REPRODUCIBILITY
±0.05%
SYRINGES (MIN./MAX.)
50 µl / 500 µl
FLOW RATE:
Minimum
3.66 pl/min
Maximum
1.91 ml/min
INJECTOR HEAD/ACTUATOR,
L x H x W
20.3 x 5.1 x 5.1 cm (8 x 2 x 2 in)
Temperature Effect on O
2
Consumption
by Organ Cell Type
Organ
Temperature
Oxygen
Consumption
Change in O
2
Consumption
% Change
Kidney
37 to 18
3.7 to 0.9
2.8
75.7
Liver
37 to 18
3.0 to 0.6
2.4
80
Heart
37 to 18
2.4 to 0.7
1.7
70.8
Brain
37 to 18
1.9 to 0.4
1.5
78.9
Muscle
37 to 18)
0.8 to 0.2
0.6
75
Skin
37 to 18
0.4 to 0.1
0.3
75
NanoCool Hand-
Held or Stereotaxic
Mounted Injector
Control Unit
Footswitch
IR Temperature Image
NanoCool at 18°C
SYRINGE PUMPS