Coleman Superfusion Bath System

Coleman Superfusion Bath System

Suitable for a variety of applications involving the study of contraction and relaxation of smooth muscle preparations, the effect of drugs that interfere with these actions, as well as those that interfere with autonomic neurotransmission.

To ensure that your system is properly configured as a functional unit that meets your application needs, please complete our Checklist and then contact Technical Services at 800-547-6766 or via email at support@hbiosci.com before placing an order. In Europe, please call +49 7665 92000 or via email at sales@hugo-sachs.de.

Item# Description U.S. List Price Quantity
73-2221 Base Unit for Superfusion Bath According to Coleman, 4-Position
73-2222 Superfusion Bath According to Coleman
73-2917 Dual Heat Exchanger for Coleman Superfusion Bath
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The Coleman Superfusion Tissue Bath System is suitable for applications involving the study of contraction and relaxation of smooth muscle preparations, the effect of drugs that interfere with these actions, and those that interfere with autonomic neurotransmission.

Features & Benefits
Applications
Modes of Operation
Required Items
Additional Equipment Required

Features & Benefits

  • Suitable for virtually any tissue sample
  • Compact, allows the study of up to four tissue preparations in parallel
  • Rapid removal of potentially toxic metabolites
  • Obviates the necessity of repeated washing procedures
  • Simple reclamation of perfusate for recirculation or collection

Applications

  • Evaluation of the potency of labile substances
  • Determining the rates of onset and offset of drug action
  • Evaluation of spasmogenic and spasmolitic agents

Modes of Operation

Flow through mode: Each tissue is superfused individually with fresh solution or solution containing the test compound. The outcoming solution is collected and goes to waste or is stored for later bioassay analysis.

Recirculating mode: Each tissue is superfused individually. The outcoming solution after superfusion is collected and used for superfusing again in the same tissue.

Cascade mode: The first tissue is superfused with fresh solution and all the subsequent tissues are superfused with the outcoming solution of


Required Items (for Functional System)*

Item # Description
73-2221 Base Unit (4-position) for Coleman Superfusion Bath
73-2222 Plexiglas Superfusion Bath (4 needed)
73-2917 Dual Heat Exchanger for Coleman Superfusion Bath
72-6432 Ecoline Roller Pump
73-0126 Tygon Pump Tubing
73-0100 REGLO Digital Roller Pump (alternative to Ecoline)
73-0125 Lauda Thermostatic Circulator, 3 L volume (if heat exchangers are used)
73-0831 Isometric Force Transducer (with mounting rod)
73-4893 Vernier Control
73-0045 PLUGSYS Housing Type 603
73-0065 PLUGSYS TAM-A Tranducer Amplifier Module
73-2696 Universal Isolated Stimulator Outupt (UISO), 115 VAC (or 73-0504, 230 VAC)
73-3716 Stimulator C, 115 VAC (or 73-3713, 230 VAC), depending on application)

* Please contact technical support for assistance. Some equipment you already have may be suitable.


Additional Equipment Required

Data acquisition hardware, process controller and PLUGSYS ACAD software, electrical stimulator

Specifications