Working Heart Upgrade for IH-5 Core System
Upgrade an IH-5 Langendorff configuration to an IH-5 Working Heart (according to Neely) System.
- Fully-ejecting working heart model for physiological cardiovascular studies in rat, guinea pig and rabbit
- Allows rapid and easy switching between Working Heart (Ejecting Heart) and Langendorff modes.
To ensure that your system is properly configured as a functional unit that meets your application needs, please complete our Checklist and then contact Technical Services at 800-547-6766 or via email at support@hbiosci.com before placing an order. In Europe, please call +49 7665 92000 or via email at sales@hugo-sachs.de. Upgrades can also be modified to meet your specific needs.
Upgrade an IH-5 Lagendorff Core System to a IH-5 Working Heart (according to Neely) System by adding a Working Heart option and one of the species-specific additions.
The IH-5 Working Heart system provides a valuable toolfor the researcher who wishes to study cardiac functionand metabolism. Because the heart is fully ejecting, it is possible to accomplish a more comprehensive monitoring of functional parameters and the calculation of external heart work and mechanical efficiency. The proprietary afterload system eliminates water column bouncing,reducing stress and damage to cardiac valves.
Researchers who know they will be upgrading to working ejecting heart in the future typically start with a Langendorff Working Heart-Ready configuration. However, a Langendorff Only configuration can easily be modified to a Langendorff Working Heart-Ready configuration. Please contact our technical team for help!
Features & Benefits
Applications
Measured Signals
Options
Species-Specific Additions
Features & Benefits
- Fully-ejecting working heart model for physiological cardiovascular studies, e.g. cardiac function and metabolism
- Allows rapid and easy switching between Working Heart (Ejecting Heart) and Langendorff modes.
Applications
- Real-time flow (cardiac output) measurement (add species-appropriate flow probes and PLUGSYS TTFM-2 Flowmeter module)
- Left ventricular pressure (LVP) measurement (add LVP Measurement option)
- Pressure-volume measurement (add Pressure-Volume Measurement option)
- High blood pressure-induced disease state simulation (add Increased Preload Pressure option)
Measured Signals
All parameters of standard Langendorff plus the following signals can be recorded:
- Preload (left atrial preload / ventricular filling pressure)
- Afterload (determining the diastolic and systolic aortic pressure)
- Left ventricular pressure or pressure-volume loops
- Cardiac output (atrial flow), aortic and coronatry flow (either Direct of by subtraction of CO-Aortic Flow)
Options
IH5-WH, Working Heart Upgrade, 230 V (73-4412) includes: |
IH5-WH Working Heart Upgrade, 115 V (73-4411) includes: |
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73-3064 | Working Heart Option to IH-5 Core System* | 73-3064 | Working Heart Option to IH-5 Core System* |
73-0020 | Blood Pressure Transducer P75 for PLUGSYS Module | 73-0020 | Blood Pressure Transducer P75 for PLUGSYS Module |
73-0065 | PLUGSYS Transducer Amplifier Module (TAM-A) | 73-0065 | PLUGSYS Transducer Amplifier Module (TAM-A) |
*The Working Heart Option includes: left atrium cannulating system with preload reservoir and preheating coil, movable atrium connection adapter and holder for P75 (preload pressure)/
Complete the Working Heart upgrade by choosing the appropriate species-specific addition:
73-4413 Working Heart Left Atrial Cannula for Rat/Guinea Pig Hearts, 2.3 mm OD (IH5-WH-RPG)
73-4414 Working Heart Left Atrial Cannula for Rabbit Hearts, 6.0 mm OD (IH5-WH-RAB)
Specifications |
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