Single-Lead ECG and MAP Measurement for IH-SR and IH-5 Langendorff or Working Heart
For single-lead ECG and MAP measurements on functional IH-SR or IH-5 Langendorff or working heart systems. ECG and MAP are recorded to be analyzed together.
The Monophasic Action Potential (MAP) electrodes work based on the principle of Franz et al whereby firm, stable contact of the MAP electrode results in a high-quality MAP. MAP recording has been utilized in cardiac physiology for decades as it allows regional assessment of the electrophysiological state of the intact heart.
For addiitonal options available for the IH-5 system, please see Multi-Lead ECG and MAP Measurement Options for IH-5 Langendorff or Working Heart.
Note: Images shown are representative.
For single-lead ECG and MAP measurements on functional IH-SR or IH-5 systems, one ECG lead is combined with one MAP electrode.
The Monophasic Action Potential (MAP) electrodes work based on the principle of Franz et al* whereby firm, stable contact of the MAP electrode results in a high-quality MAP. MAP recording has been utilized in cardiac physiology for decades as it allows regional assessment of the electrophysiological state of the intact heart.
For additional options available for the IH-5 system, please see Multi-Lead ECG and MAP Measurement Options for IH-5 Langendorff or Working Heart.
* Franz MR, Burkhoff D, Spurgeon H, Weisfeldt ML, Lakatta EG (1986). In vitro validation of a new cardiac catheter technique for recording monophasic action potentials. Eur Heart J , 7: 34-41.
Features & Benefits
- Mini monophasic action potential electrodes for epicardial and endocardial recording, with dedicated holders
- Precision MAP electrodes with dedicated holders allow easy positioning on the heart
- Small electrodes allow multiple ECG and MAP signals to be recorded even on mouse hearts
- Mini ECG electrodes with dedicated holders
- Flexible ECG electrodes follow the heartbeat, dedicated holders allow easy positioning on the heart
- Optimized coaxial pacing electrode
- Reduced stray fields from the pacing electrode for more accurate recordings
Applications
MAP recording is essential to researchers who study:
- Atrial fibrillation
- Arrhythmias
- Anti-arrhythmic drugs
- Ischemia
- Depolarization and repolarization cycles
- Activation time
- Mechanisms of action of various drugs
Options
For the addition of MAP recording to your functional isolated perfused heart system, we have a number of options:
| Option | Measurement | Species | System Compatibility | Included Items |
| 73-4025 | Single Epicardial MAP | Mouse | IH-SR | Micro MAP-tip electrode (73-3840) Link for Higher Load Capacity, for Two Arms with 5 mm Mini Balls (73-0564) MAP Opposite Holder to Maintain Mouse Heart in Position (73-3858) Connection Cable for MAP Electrode to BPA Amplifier (73-0152) PLUGSYS Biopotential Amplifier (BPA) Module (73-0153) |
| 73-4026 | Single Epicardial MAP | Rat, Guinea Pig | IH-SR | Mini MAP-tip electrode (73-0150) Holder for MAP Electrode for IH-SR System (73-0151) MAP Opposite Holder to Maintain Rat or Guinea Pig Heart in Position (73-2989) Connection Cable for MAP Electrode to BPA Amplifier (73-0152) PLUGSYS Biopotential Amplifier (BPA) Module (73-0153) |
| 73-4421 | Single Epicardial MAP |
Rat, Guinea Pig, Rabbit | IH-5 | Mini MAP Tip Electrode (73-0150) Link for Higher Load Capacity, for Two Arms with 5 mm Mini Balls (73-0564) Mini Ball Joint Holder (73-0563) Holders for MAP Electrode for Precise Placement and Stabilization (73-0151) Large Opposite Holder (Spoon) for Larger Hearts for IH-5 (73-3755) PLUGSYS Biopotential Amplifier (BPA) Module (73-0153) Connection Cable for MAP Electrode to BPA Amplifier (73-0152) |
| 73-4027 | Single Endocardial MAP | Rat, Guinea Pig, Rabbit | IH-SR, IH-5 | Intracardial MAP-tip electrode with Holders (73-3715) Connection Cable for MAP Electrode to BPA Amplifier (73-0152) PLUGSYS Biopotential Amplifier (BPA) Module (73-0153) |
| 73-4422 | ECG Lead II | Mouse to Rabbit | IH-SR, IH-5 | Two Contact ECG Electrodes (73-0200) Mini Ball Joint Holder System for Universal IH-System Mounting ECG Amplifier Connection Cable |
MAP Electrodes
The MAP electrodes required for each application, species and system are included in the options above.
Micro MAP-Tip Electrode (73-3840) for single epicardial MAP on IH-SR with mouse heart includes the electrode, spring wire and pack of sponges, as well a 2 mm male connector. The MAP electrode opposite holder (73-3858) needs to be attached with a certain pressure to the heart on the opposite side to hold the heart in position.
Mini MAP-Tip Electrode (73-0150) for single epicardial MAP on IH-SR (rat, guinea pig heart) or IH-5 (rat, guinea pig, rabbit heart) comes with two male connectors and includes one pack of sponges. The MAP electrode opposite holder (73-2989) holds the rat or guinea pig heart in place at a certain pressure.
MAP Electrode for Intracardial MAP (73-3715) for endocardial MAP on IH-SR or IH-5 (rat, guinea pig, rabbit heart) includes necessary holders.
For more details about these packages, please contact Technical Support.
| Specifications | 73-0174 | 73-0177 |
|---|---|---|
| Ball Joint Holder Length | 23 mm | 23 mm |
