Perfusion Solution Electrochemical Monitoring for All Isolated Organ Systems

BIOSEN Measurement System for pH, pO2 and pCO2

This option permits precise continuous monitoring and measurement of three key parameters, pO2, pH and pCO2, in liquid media or perfusate. Monitoring is accomplished using ion-sensitive, chemosensor-based, flow-through electrodes.

The electrodes require a dedicated pulsation-free peristaltic pump to deliver a constant flow of perfusate through the electrode at flow rates in the range of 0.5 to 2 ml/min. Because of the high impedance of these sensors, screening or shielding of the measuring circuit is required to protect against electrostatic discharges and other electrical disturbances.

Item# Description U.S. List Price Quantity
73-4287 In-line Perfusion Solution Electrochemical Monitoring for Isolated Organ System, 230 V. Requires Amplifier and Sensors, not included
73-4304 In-line Perfusion Solution Electrochemical Monitoring for Isolated Organ System 115 V. Requires amplifier and sensors, not included
73-4029 pO2 Measurement Sensor and Amplifier for 73-4287 and 73-4304
73-4031 pCO2 Measurement Sensor and Amplifier for 73-4287 and 73-4304
73-4030 pH Measurement Sensor and Amplifier for 73-4287 and 73-4304
73-4195 Microelectrode Shielding Case for Three Electrodes (pH, pO2, pCO2)
73-0207 Mounting Plate for Three-Electrode Shielding Case
73-4196 Microelectrode Shielding Case for Single Electrode (pO2 or pCO2)
73-3000 Mounting Base for Single Electrode Shielding Case Sensors for pO2 Measurement
73-4189 Oxygen Flow-Through Electrode, 1/16" Fittings
73-4191 CO2 Flow Through Electrode, 1/16” Fittings Sensors (for pH Measurement)
73-4190 pH Flow Through Electrode, 1/16” Fittings
73-4197 pH Mini Flow Through Electrode Set, 1/16" fittings. Includes: flow through electrode, solid state
73-2998 Leak Free pH Flow Through Reference Electrode Set for Millivolt Adapter and pHMM Module Amplifiers & Adapters
73-0210 Oxygen Partial Pressure Module (OPPM)
73-0212 Electrometer Module (EMM)
73-0215 pH Measurement Module (pHMM)
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This option permits precise continuous monitoring and measurement of three key parameters, pO2, pH and pCO2 in liquid media or perfusate. Monitoring is accomplished using ion-sensitive, chemosensor-based, flow-through electrodes. The electrodes require a dedicated pulsation-free peristaltic pump to deliver a constant flow of perfusate through the electrode at flow rates in the range of 0.5 to 2 ml/min.

Because of the high impedance of these sensors, screening or shielding of the measuring circuit is required to protect against electrostatic discharges and other electrical disturbances.

Continuous measuring pH, pO2 and pCO2 of the perfusion solution in an isolated organ system allows the user to control these parameters over the course of the experiment. It is especially important to monitor these parameters throughout the course of drug studies as any change in these values indicates a significant effect of the drug being tested.

Components can be purchased separately or you can choose an electrochemical monitoring system plus the sensor/amplifier packages you need. (Specifically, combine 73-4287 or 73-4304 with 73-4029, 73-4030 and/or 73-4031.)

Applications

  • Measurement of organ O2 consumption, CO2 production and/or pH changes 

Features & Benefits

  • Enables continuous measurement of pH, pO2, and pCO2 in perfusate
  • Smooth side stream flow through electrodes with use of peristaltic pump
  • Noise-free design (when used with the Shielding Case)
  • Measure parameters in the reservoir (pre-organ) and in the effluent (post-organ) allowing measurement of O2 exchange, CO2 production and pH change

Included Items

Perfusion Solution Electrochemical Monitoring Systems

Part # Description Included Items
73-4287 Monitoring System, 230 V
  •  73-4195 Microelectrode Shielding Case for Three Electrodes (pH, pO2, pCO2)
  •  73-0207 Mounting Plate for Three-Electrode Shielding Case
  •  73-0114 REGLO Analog 4-Channel Pump MS-4/8-100, 230 VAC, 50 Hz
  •  73-0126 3-stop Collared Tygon® E-Lab Tubing, 1.22 mm ID, max flow 8.8 ml/min, pkg. of 12
73-4304 Monitoring System, 115V
  •  73-4195 Microelectrode Shielding Case for Three Electrodes (pH, pO2, pCO2)
  •  73-0207 Mounting Plate for Three-Electrode Shielding Case
  •  73-0113 REGLO Analog 4-Channel Pump MS-4/8-100, 115 VAC, 60 Hz
  •  73-0126 3-stop Collared Tygon® E-Lab Tubing, 1.22 mm ID, max flow 8.8 ml/min, pkg. of 12


Measurement Sensors and Amplifiers

Part # Description Included Items
73-4029 pO2 Measurement Sensor and Amplifier
  •  73-4189 Mini Flow-Through O2 Electrode, 1/16" Fittings, for use with OPPM
  •  73-0210 PLUGSYS Oxygen Partial Pressure Module (OPPM)
73-4030 pH Measurement Sensor and Amplifier
  •  73-4190 pH Flow Through Electrode, 1/16” Fittings
  •  73-2998 Leak Free pH Flow Through Reference Electrode Set
  •  73-0215 PLUGSYS pH Measurement Module (pHMM)
73-4031 pCO2 Measurement Sensor and Amplifier
  •  73-4191 CO2 Flow Through Electrode, 1/16” Fittings Sensors for pH Measurement
  •  73-0212 PLUGSYS Electrometer Module (EMM)

Additional Items If Not Purchasing a System

  • Dedicated peristaltic pump (such as REGLO Analog Pump 73-0114 or 73-0113) and appropriate pump tubing (73-0206) 

Note: Various microelectrodes and associated components are available. Not all options listed. Please contact us to discuss your application so that we can assist you with the best possible solution.

Specifications