MidiVent Ventilator for Large Mice and Small Rats (Model 849) - Single Animal, Volume Controlled

MidiVent Ventilator for Large Mice and Small Rats (Model 849) - Single Animal, Volume Controlled

The MidiVent Model 849 Ventilator is a quiet, compact and light weight ultra low volume ventilator. While it was designed specifically for large mice, the Midivent can be used for any animal (e.g. small rats, shrew, hamster) which requires tidal volumes in the range of 60 to 700 µl and respiratory rates of 60 to 400 breaths per minute.

The extremely light weight and compact construction, in addition to the convenient rod clamp, allow the MidiVent ventilator to be positioned directly next to the animal.

• Ideal for large mice and small rats up to 100 grams
• Stroke volume range from 60 to 700 µl
• Ventilation rate from 60 to 400 breaths/minute
• Simple adjustment of stroke volume while running
• Valveless piston pump, no valves to clog
• Very small instrument/circuit dead space volume
• Compact construction, easy to install close to animal
• No vibrations, very low noise

See Full Description for complete details.

Item# Description U.S. List Price Quantity
73-4120 MOUSE VENTILATOR MIDIVENT TYPE 84), WITH POWER SUPPLY 110V, HIGH VOLUME
73-4119 MOUSE VENTILATOR MIDIVENT TYPE 849, WITH POWER SUPPLY 230V, HIGH VOLUME
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The MidiVent Model 849 Ventilator is a quiet, compact and light weight ultra low volume ventilator. While it was designed specifically for large mice, the Midivent can be used for any animal (e.g. small rats, shrew, hamster) which requires tidal volumes in the range of 60 to 700 µl and respiratory rates of 60 to 400 breaths per minute.• Ideal for large mice and small rats up to 100 grams
• Stroke volume range from 60 to 700 µl
• Ventilation rate from 60 to 400 breaths/minute
• Simple adjustment of stroke volume while running
• Valveless piston pump, no valves to clog
• Very small instrument/circuit dead space volume
• Compact construction, easy to install close to animal
• No vibrations, very low noise

The MidiVent Ventilator is a constant-volume respiration pump operating on the Starling principle. Unlike conventional units for larger animals, this ventilator employs a rotary plunger and has no valves. During each ventilation cycle, the plunger performs a synchronized forward and rotating movement. Cleverly arranged bores and channels in the cylinder and plunger control inspiration and expiration during each stroke of the plunger.

The extremely light weight and compact construction, in addition to the convenient rod clamp, allow the MidiVent ventilator to be positioned directly next to the animal. Typical setups with larger ventilators produce large tubing and instrument dead space volumes. These larger volumes introduce greater system compliance which can affect the accuracy with which the full tidal volume is introduced into the animal's lungs. With the MidiVent, the tidal volume error due to system compliance is reduced to 5 µl.

Tidal volume and respiration rate can be set exactly to the values required for mouse ventilation. The level of precision and control available to the investigator minimizes the danger of hyperventilation or hypoventilation.
The tidal volume can be varied continuously from 60 to 700 ul during operation without having to interrupt ventilation. The respiration rate is also continuously adjustable from 60 to 400 strokes/min. The expired air can be recovered at the collection port for sampling, recycling or for the generation of a positive end-expiratory pressure (PEEP). Room air or any non-explosive gas mixture can be used to feed the pump intake using the special connection tubing PY2 73-3077.

A multi-gas inlet adapter is available for the MidiVent so that alternate gas mixtures and nebulized substances are delivered to thr MidiVent inlet port at atmospheric pressure. The adapter provides ports for multiple selectable gas mixture (hypoxic, anesthetic...) and a port for the Aerosol Nebulizer.

The system is supplied with a 1.5 mm OD tracheal cannula and a 1.5 mm OD intubation cannula for the mice. For other size animals, additional intuubation or tracheal cannula sizes may be needed.

Specifications73-412073-4119
AC Adapter Weight English0.7 lb0.7 lb
AC Adapter Weight Metric0.3 kg0.3 kg
CertificationsCECE
Control ModesVolumeVolume
Depth English7.9 in7.9 in
Depth Metric20 cm20 cm
Displaynonenone
Gas SupplyRoom air or non-flammable mixed gasRoom air or non-flammable mixed gas
Height English3.1 in3.1 in
Height Metric8 cm8 cm
I E Ratio1:11:1
I E Ratio UOM%%
ModelMidiVentMidiVent
Net Weight English2.2 lb2.2 lb
Net Weight Metric1 kg1 kg
Number of Animals11
PEEPProvided via attachment of water columnProvided via attachment of water column
Respiration Rate Maximum400 breaths/min400 breaths/min
Respiration Rate Minimum60 breaths/min60 breaths/min
Respiratory Rate NoteContinuously adjustable from 60 to 400 breaths/minContinuously adjustable from 60 to 400 breaths/min
Sigh Frequencynonenone
Sigh PressureNot availableNot available
SpeciesLarge Mice, Small RatsLarge Mice, Small Rats
Stroke Volume NoteContinuously adjustable from 0 to 130 µlContinuously adjustable from 0 to 130 µl
Tidal Volume Maximum700 ul/stroke700 ul/stroke
Tidal Volume Minimum60 ul/stroke60 ul/stroke
Voltage Range110 VAC230 VAC
Weight Range Maximum100 g100 g
Weight Range Minimum5 g5 g
Width English3.9 in3.9 in
Width Metric10 cm10 cm

HannahT. Nickles ,  Migle Sumkauskaite ,  Xin Wang ,  Ingmar Wegner ,  Michael Puderbach ,  Wolfgang M. Kuebler (2014 ) Mechanical ventilation causes airway distension with proinflammatory sequelae in mice Am J Physiolo Lung Cell Mol Physiol