Small Animal Physiological Monitoring System

The Small Animal Physiological Monitoring System (HPMS) is an instrument that measures multiple physiological parameters on one single small platform.

The system comes complete with heated monitoring platform, Android tablet with a protective sleeve and stand, wireless communication module, rectal probe, and electrode gel. Adapter and cable for the tablet and wireless connection cable are included. These components are all supplied in a sturdy case for storage and transport.

The platform includes four electrocardiogram (ECG) surface electrodes, a respiration sensor and a heated surface that can be used at a set temperature or in a homeothermic setup using the rectal probe. Additional options to monitor oxygen saturation (SpO₂), blood pressure and exhaled CO₂ can be purchased separately.

Monitoring software is pre-installed on the Android tablet. All data is transferred to the Android tablet by wireless for display and saving. A real-time display provides numeric values as well as waveforms that can be customized by the user. Multiple signals can be displayed on each of three graphs.

At the end of experiments, recorded data can easily be transferred to any computer for analysis. Scripts and utilities are provided to convert data in LabChart or CSV format and to display signals in Excel and MATLAB.

Features & Benefits

• Monitors temperature, electrocardiogram (ECG), and respiration, and optionally, oxygen saturation (SpO₂), blood pressure and exhaled CO₂
• Small footprint for mouse or rat
• Minimal setup time at the beginning of procedures
• Heated platform
• Intuitive touchscreen
• Reduces the required space and the number of wires around the animal.
      - A single data/power cable connects to a small wireless communication module 
• Real-time display provides numeric values as well as waveforms that can be customized by the user. 
      - Multiple signals can be displayed on each of the three graphs
• Recorded data can easily be exported for further analysis 
      - Scripts and utilities provided to convert data in LabChart or CSV format and to display signals in
        Excel and Matlab
• Head fixation kit for mouse available for stereotaxic applicatons

 Included Components 

• Heated monitoring platform (for rat or mouse)
• Android tablet with stand and protective case
• USB adapter and cable for android tablet
• Wireless communication module with power supply and power cord
• 9-pin connection cable to connect communication module and monitoring platform
• Rectal probe
• Electrode gel
• User's manual

Physiological Parameters Measured

• ECG: integrated electrodes under the paws & external electrodes
• Respiration: waveform acquired with a sensor under the animal
• Heart and Breath Rate: real-time display from the ECG and respiration waveform
• Warming and Temperature: heated platform and rectal probe for precise control and monitoring
• Blood Pressure (option): connection for a pressure catheter
• SpO₂ (option): pulse oximetry and oxygen saturation with a paw/tail sensor
• Exhaled CO₂ (option): gas ports for precise CO₂ measurements (with an external ventilator)

System Information

Heated Platform

• Easy to clean surface
• 10 cm x 21 cm x 2.5 cm (mouse)
• 12 cm x 27 cm x 2.5 cm (rat)
• External ports – Rectal temperature, pressure catheter, ECG electrodes, SpO₂ sensor
• ECG electrodes
• Respiration sensor
• Warming zone – 0.1^oC resolution
• Single data/power cable – Link to a compact wireless module with 4 analog outputs
• Exhaled CO₂ ports

Tablet

• 8” Android tablet (10.1” available)
• High resolution touchscreen display: pinch to zoom on waveforms (works with surgical gloves)
• Capacity of over 400 hours of saved data
• 5 to 8 hours battery life
• Advanced display interface
  • 1 to 5 second waveforms - Select any signal to display
  • 1 to 30 minute trends - View temperature, heart & breath rate trends, and numeric values
  • Easy data saving - Add notes, save and export data for an easy analysis

Wireless Communication Module

• Wireless and analog outputs are in a separate enclosure to avoid interferences
• 9 cm x 11 cm x 2.5 cm
• 100 to 240 V power supply
• 15 to 25 meters typical range between the communication module and the display unit 

Analog Outputs

• 4 configurable outputs
• BNC connectors, ±5 V range
• 1 kHz, 16-bit refresh rate

Data Analysis

• .csv conversion tool
• MATLAB^® & Excel^® import and display scripts
• Compatible with third-party analysis software (LabChart)