Perfusion Solution Electrochemical Monitoring for All Isolated Organ Systems
This option permits precise continuous monitoring and measurement of three key parameters, pO2, pH and pCO2, in liquid media or perfusate.
Monitoring is accomplished using ion-sensitive, chemosensor-based, flow-through electrodes.The electrodes require a dedicated pulsation-free peristaltic pump to deliver a constant flow of perfusate through the electrode at flow rates in the range of 0.5 to 2 ml/min. Because of the high impedance of these sensors, screening or shielding of the measuring circuit is required to protect against electrostatic discharges and other electrical disturbances.
This option permits precise continuous monitoring and measurement of three key parameters, pO2, pH and pCO2 in liquid media or perfusate. Monitoring is accomplished using ion-sensitive, chemosensor-based, flow-through electrodes. The electrodes require a dedicated pulsation-free peristaltic pump to deliver a constant flow of perfusate through the electrode at flow rates in the range of 0.5 to 2 ml/min.
Because of the high impedance of these sensors, screening or shielding of the measuring circuit is required to protect against electrostatic discharges and other electrical disturbances.
Continuous measuring pH, pO2 and pCO2 of the perfusion solution in an isolated organ system allows the user to control these parameters over the course of the experiment. It is especially important to monitor these parameters throughout the course of drug studies as any change in these values indicates a significant effect of the drug being tested.
Components can be purchased separately or you can choose an electrochemical monitoring system plus the sensor/amplifier packages you need. (Specifically, combine 73-4287 or 73-4304 with 73-4029, 73-4030 and/or 73-4031.)
Applications
- Measurement of organ O2 consumption, CO2 production and/or pH changes
Features & Benefits
- Enables continuous measurement of pH, pO2, and pCO2 in perfusate
- Smooth side stream flow through electrodes with use of peristaltic pump
- Noise-free design (when used with the Shielding Case)
- Measure parameters in the reservoir (pre-organ) and in the effluent (post-organ) allowing measurement of O2 exchange, CO2 production and pH change
Included Items
Perfusion Solution Electrochemical Monitoring Systems
| Part # | Description | Included Items |
| 73-4287 | Monitoring System, 230 V |
|
| 73-4304 | Monitoring System, 115V |
|
Measurement Sensors and Amplifiers
| Part # | Description | Included Items |
| 73-4029 | pO2 Measurement Sensor and Amplifier |
|
| 73-4030 | pH Measurement Sensor and Amplifier |
|
| 73-4031 | pCO2 Measurement Sensor and Amplifier |
|
Additional Items If Not Purchasing a System
- Dedicated peristaltic (roller) pump and appropriate pump tubing (73-0206)
Note: Various microelectrodes and associated components are available. Not all options listed. Please contact us to discuss your application so that we can assist you with the best possible solution.
