IH-5 Core System Options

IH-5 Core System Options

Additions to the IH-5 Core System for species-specific Langendorff Only or Langendorff Working Heart-Ready configurations.

Options must be selected for a functional unit.

To ensure that your system is properly configured as a funtional unit that meets your application needs, please complete our Checklist and then contact Technical Services at 800-547-6766 or via email at support@hbiosci.com before placing an order. In Europe, please call +49 7665 92000 or via email at sales@hugo-sachs.de. Upgrades can also be modified to meet your specific needs.

Item# Description U.S. List Price Quantity
73-4399 Additions to the IH-5 Core System for Rat/Guinea Pig Hearts (IH-5 RGP)
73-4400 Additions to the IH-5 Core System for Rabbit Hearts (IH-5 RAB)
73-2806 PLUGSYS Servo Controller for Perfusion (SCP)
73-4435 Perfusion Pressure Control with Starling Resistor (STARLING-IH5)
73-4401 Heart Chamber for IH-5 Core System for Cardiovascular Studies (IH5-HC-CARDIO)
73-4402 Heart Chamber for IH-5 Core System for Electrophysiology (IH5-HC-EPHYS)
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Additions to the IH-5 Core System for species-specific Langendorff Only or Langendorff Working Heart-Ready functional units

An IH-5 Langendorff functional unit requires the addition of core options to the selected core system (either 73-4397 or 73-4398). Specifically, the core system requires the addition of a selection of one of the perfusion pressure controllers (SCP or STARLING-IH5), one of the species-specific options, and an application-appropriate heart chamber.

 Langendorff Only Configuration
 (Add these core options to 73-4397 or 73-4398)
 Langendorff Working Heart-Ready Configuration
(Add these core options to 73-4397 or 73-4398)
 Species Specific Addition (choose one or both)
• 73-4399 for Rat/Guinea Pig Hearts (IH5-RGP)
• 73-4400 for Rabbit Hearts (IH5-RAB)

 Species Specific Addition (choose one or both)
• 73-4399 for Rat/Guinea Pig Hearts (IH5-RGP)
• 73-4400 for Rabbit Hearts (IH5-RAB)

 Constant Pressure/Flow Controller (required)
73-2806 SCP PLUGSYS Servo Controller Module 

 Perfusion Pressure Control (required)*
73-4435 STARLING-IH5 Starling Pressure Controller

Heart Chamber (choose one)
• 73-4401 for Cardiovascular Studies (IH5-HC-CARDIO)
• 73-4402 for Electrophysiology Studies (IH5-HC-EPHYS)**

Heart Chamber (choose one)
• 73-4401 for Cardiovascular Studies (IH5-HC-CARDIO)
• 73-4402 for Electrophysiology Studies (IH5-HC-EPHYS)**

The core options selected depend on:

  1. If you want a Langendorff Only configuration or a Working Heart-Ready Langendorff configuration. (If you expect to upgrade from Langendorff to Working Heart in the future, we recommend you start with the working heart-ready configuration.)
  2. The species to be studied, i.e., mouse, rat or guinea pig
  3. Your application, i.e., cardiovascular studies or electrophysiology studies

*Additionally requires a species-specific direct flow measurement option.

**Choose this option if the multi-ECG ring and/or circular MAP ring will be used


Pressure Controller Options

SCP Servo Controller for Perfusion (73-2806)

This constant pressure/flow controller perfuses a heart in constant pressure mode. Required for Langendorff Only configuration.

  • Allows operation in constant pressure or constant flow with simple switch
  • Provides accurate control of perfusion pressure or flow, even at very low flow rates
  • Flexible perfusion circuit setup adjustes to suit individual perfusion conditions

Additional measured signals/calculated parameters:

  • Indirect coronary flow measurement
  • Calculation of coronary resistance

Additional items required:

  • PC-based data acquistion system

 

STARLING-IH5 Perfusion Pressure Controller with Starling Resistor (73-4345)

This perfusion pressure controller with Starling resistor provides constant pressure perfusion of the heart in Langendorff mode and acts as an afterload system in the working heart mode. Required for Langendorff Working Heart-Ready configuration.

  • Uses Teflon membrane flow resistor, manometer and pressure syringe to create a pressure-controlled valve in the aortic block
  • Mechanical device that does not provide flow information and does not alter the pump flow rate
    • Flow rate is set high on the pump and only the flow that generates the set perfusion pressure is delivered to the heart while the remainder exits via the valve and returns to the reservoir.
  • Must choose direct coronary flow measurement to measure coronary flow

Additional measured signal/calculated parameters:

  • Coronary flow data

 Includes:

  • Aortic Block Base Unit with Flange-Mounted Adjustable Flow Resistance
  • Pressure Syringe with Mounting Bracket
  • Manometer

Additional items required:

  • TTFM-2 and appropriate flow probes for direct flow measurement
  • PC-based data acquisition system
  • Pump, transducer and amplifiers for additional measurements

Species Specific Options

IH5-RGP Additions to IH-5 Core System
for Rat and Guinea Pig Hearts (73-4399) includes:
IH5-RAB Additions to IH-5 Core System
for Rabbit Hearts (73-4400) includes:
73-3072 Aortic Cannula for Rat/Guinea Pig Hearts to IH-5, set of 2, OD 3.0 and 2.5 mm 73-0719 Aortic Cannula for Rabbit Hearts to IH-5, OD 2.3 mm, set of 3, OD 3.0, 4.0 and 5.0 mm
73-3074 Tubing Set for Rat/Guinea Pig Heart on IH-5
Tubing Set for Rabbit Heart on IH-5
73-3456 Tubing Set for Jacketed Buffer Reservoir with Fluid Line Shutoff Valves   Tubing Set for Jacketed Buffer Reservoir with Fluid Line Shutoff Valves
73-3441 Reservoir Jacketed for Buller Solution, with Frit and Bottom Drain, 2 L 73-0322 Reservoir Jacketed for Buffer Solution, with Frit, 6 L
73-4463 Balloon Kit for Rat/Guinea Pig Hearts to IH-5 Core System, includes 10 balloons, size 5 (0.1 ml volume), spindle set and holder 73-0323 Balloon Kit for Rabbit Hearts for IH-, includes 5 balloons, size 12 (1.3 ml volume), 5 balloons, size 13 (1.6 ml volume), spindle set and holder

 

Specifications73-2806
AccessoriesOperating Instructions, Screwdriver, Output Cable to Pump
Actual Value Input0 - 10 V via System Bus
Ambient ConditionsLaboratory Indoors
ConnectorDIN 41612, 96-pin VG
ConstructionPlug-in Module for a PLUGSYS
Control Gain1 - 50, Adjustable
Control Voltage0 - 10 V to Operate the Pump
Derivative Factor0.1 - 100, Adjustable
DescriptionServo Controller for Perfusion (SCP) Type 704
Digital IndicationRange -1999 to +1999, Selectable for Actual Value, Setpoint, or Control Output Signal
FunctionElectronic PID Controller for Physiological and Pharmacological Research
Integral Factor0.05 - 10, Adjustable
PLUGSYS Width*2 slot units
Power Supply5 V, 0.3 A from PLUGSYS
Recorder Output0 - 10 V, BNC Socket
Setpoint0 - 5 V, Adjustable
Weight (Metric)0.3 kg