Fiber Optic Perfusion Solution Monitoring (PreSens)
PreSens fiber optic minisensors and space-saving digital-phase transmitters for precise and stable temperature-compensated measurement of pO2, pCO2 and pH in ex vivo organ perfusion systems.
These high performance systems can be used for discrete rapid checks or continuous measurements, even in multi-day perfusion studies.
- State-of-the-art system provides unprecedented performance and precision.
- Temperature compensation ensures accurate measurements even in environments or experiments with temperature variations.
- Sterile, beta-irradiated flow-through cells.
Precise and stable temperature-compensated measurement of pO2, pCO2 and pH in ex vivo organ perfusion systems is now possible using PreSens fiber optic minisensors and space-saving digital-phase transmitters. These high performance systems can be used for discrete rapid checks or continuous measurements, even in multi-day perfusion studies.
Features
- State-of-the-art system provides unprecedented performance and precision.
- Temperature compensation ensures accurate measurements even in environments or experiments with temperature variations.
- Sterile, beta-irradiated flow-through cells.
Easy to Set Up, Easy to Use
Simply add the flow-through cell for the parameter you wish to measure with a T-piece to your perfusion line and connect to the associated transmitter with a polymer optical fiber. Connect a Pt100 temperature probe for temperature compensation and temperature measurement. Then connect the transmitter to a PC using the included USB cable to record and view data via Measurement Studio 2 Software.
Multiple Measurements
To measure two or three parameters simultaneously, add the flow-through cells in series to the measuring channel in a bypass*, ending the sequence with a Pt100 temperature probe. Connect the appropriate transmitter to the sensor using a polymer optical fiber. The USB port on each transmitter connects to the PC.
For a multi-channel system only one Pt100 temperature probe is required. It is recommended to have the temperature probe at the end of the sequence of flow-through cells (after the sensors) so that no air bubbles are trapped.
*For perfusion studies with continuous flow rates below 2 ml/min the sensors can be placed directly inline of the afferent or efferent cannulae. For perfusion flow rates above 2 ml/min or for non-continuous flow rates (e.g., constant pressure perfusion) a bypass or side stream flow line must be created with a fluid T-connection and a peristaltic pump drawing perfusate through the sensor(s) at a continuous rate ideally between 1 to 2 ml/min.
System Components
Flow-Through Cells
PreSens flow-through cells are parameter specific fiber optic sensors (pO2, pCO2 and/or pH) that interface between the solution and the polymer optical fiber. They feature a water-tight connection fo rthe optical fiber and Luer lock connector sfor easy interconnection to the fluid circuit. The three parameters can be measured continuously in a bypass circuit with the addition of an appropriate peristaltic pump to the setup.
Include: Fiber optic transmitter, USB mini cable, and PC recording software for single- and multi-channel devices and all necessary tubing to secrue POF into flow-through cell.
PreSens Measurement Studio 2 Software
The PreSens Measurement Studio 2 Software is included with all transmitters (pO2, pCO2 and pH) and records parameter values from one or more PreSens transmitters through a USB connected Windows® 7 or 10 OS-based computer. Data management for sensors, measurement files and users, as well as export of files into .csv format, can be accomplished easily with just a few clicks. The intuitive measurement control facilitates precise measurements with multiple devices simultaneously.
Pt100 Temperature Probe for Temperature Compensation
The Pt100 temperature sensor is integrated into any single- or multi-channel flow-through circuit and connected to any one of the transmitters. Solution temperature affects the measured values of pO2, pCO2 and pH. To accurately measure these parameters, especially during chronic perfusion studies, it is important that solution temperature be measured simultaneously. The Studio 2 software records the temperature and calculates the compensated values in real time.
Cable length 5 M, length of temperature probe 40 mm, OD 1.9 mm. Includes connectors and fittings to insert probe into perfusion circuit.
Single-Channel Fiber Optic Transmitters
PreSens transmitters convert an optical signal (light) into a digital value which is recorded using the Measurement Studio 2 Software that is included with all transmitters. These transmitters can be assembled in a few easy steps and are extremely space-saving. Because the devices are powered via USB, no additional power connections, cables or adapters are required.
Polymer Optical Fiber
The polymer optical fiber transfers excitation light to the sensor and the sensor response back to the transmitter.
Analog Output Extension
This extension allows continuous, simultaneous recording of PreSens measured values, in addition to other significant values, using any DataAcquisition System (DAQ) such as HSE ISOHEART and PULMODYN, ADI PowerLab or DSI PoNeMah.
The analog output extension is connected via USB to the PC. All the digital values (pO2, pCO2, pH,temperature) which are taken from the PreSens transmitters and displayed in the Measurement Studio 2 software, can be sent to the analog output extension. An external DAQ System synchronizes recording of pO2, pCO2 and pH together with all other collected signals such as pressures, flows, ECG, etc., to one time scale, for easier evaluation of experiment results.
Each analog converter outputs two user-selectable signals to an external DAQ, or other device, for two software selectable parameters. Two analog output extensions can be used simultaneously if you require 3 to 4 analog representations (outputs) of the measured parameters. Includes USB-RS485-RJ 4-4 cable.
PreSens Adapter Kit
This is a replacement fittings package for fiber optic pO2, pCO2 or pH measurement. Includes all necessary adapters, Luer connectors, T-pieces and tubing.
