Millar MPVS Ultra Pressure-Volume Systems

The MPVS Ultra simultaneously and continuously measures high-fidelity left ventricular pressure and relative volume from the intact beating hearts of animals ranging in size from transgenic mice to cats. Using the MPVS Ultra, cardiovascular pressure and volume signals can be plotted against each other in real time, generating the characteristic pressure-volume (P-V) loops that are an excellent illustration of the cardiac cycle in normal or diseased conditions of the living heart. MPVS Ultra is the only complete solution for measuring real-time cardiovascular pressure and volume in small and large animal models with an industry-leading seven volume segments.

MPVS Ultra Components

• MIKRO-Tip® P-V catheters
• P-V signal conditioning hardware with innovative software-controlled user interface
• PVAN Ultra™ data analysis software
• Rho cuvette for volume calibration
• Data acquisition system (Choose from available Harvard Apparatus DAQ systems)
• Connection cables
• Computer (not included)

Features

• Real-time pressure-volume measurement at the source
• High-frequency response
• No motion artifact or damping of pressure signal
• Minimally invasive
• Small and large animal capabilities
• Software controlled user interface
• Comprehensive, easy-to-use analysis software

 Applications

• Baseline P-V loop analysis
• Occlusion P-V loop analysis
• Phenotyping gene manipulations
• Cardiac hypertrophy
• Cardiac failure
• Cardiovascular remodeling
• Toxicology
• Pharmacology (rapid drug screening)
• Cardiac resynchronization therapy
• Surgical interventions
• Ischemia/reperfusion studies

Please contact your local Harvard Apparatus Representative or Technical Services to configure a system to your requirements.