MidiVent Ventilator for Large Mice and Small Rats (Model 849), Single Animal, Volume Controlled

MidiVent Ventilator for Large Mice and Small Rats (Model 849), Single Animal, Volume Controlled

The MidiVent Model 849 Ventilator is a quiet, compact and light weight ultra low volume ventilator. While it was designed specifically for large mice, the Midivent can be used for any animal (e.g. small rats, shrew, hamster) which requires tidal volumes in the range of 60 to 700 µl and respiratory rates of 60 to 400 breaths per minute.

The extremely light weight and compact construction, in addition to the convenient rod clamp, allow the MidiVent ventilator to be positioned directly next to the animal.

  • Ideal for large mice and small rats up to 100 grams 
  • Stroke volume range from 60 to 700 µl
  • Ventilation rate from 60 to 400 breaths/minute 
  • Simple adjustment of stroke volume while running 
  • Valveless piston pump, no valves to clog 
  • Very small instrument/circuit dead space volume 
  • Compact construction, easy to install close to animal 
  • No vibrations, very low noise

See Full Description for complete details.

Item# Description U.S. List Price Quantity
73-4119 Mouse MidiVent Ventilator, Type 849, with 230 V Power Supply, High Volume
73-4120 Mouse MidiVent Ventilator, Type 849, with 110 V Power Supply, High Volume
73-3077 Ventilation Connection Kit for MiniVent, MicroVent, MidiVent and Model 687 Mouse Ventilators
73-4008 Trigger Output Option for MiniVent, End of Inspiration
73-4013 Tirgger Output Option for Minivent, End of Expiration
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The MidiVent Model 849 Ventilator is a quiet, compact and light weight ultra low volume ventilato designed specifically for large mice. it can be used for any animal (e.g. small rats, shrew, hamster) which requires tidal volumes in the range of 60 to 700 µl and respiratory rates of 60 to 400 breaths per minute.

Key Features

  • Ideal for large mice and small rats up to 100 grams
  • Stroke volume range from 60 to 700 µl
  • Ventilation rate from 60 to 400 breaths/minute 
  • Simple adjustment of stroke volume while running 
  • Valveless piston pump, no valves to clog 
  • Very small instrument/circuit dead space volume 
  • Compact construction, easy to install close to animal 
  • No vibrations, very low noise


How it Works

The MidiVent Ventilator is a constant-volume respiration pump operating on the Starling principle. Unlike conventional units for larger animals, this ventilator employs a rotary plunger and has no valves. During each ventilation cycle, the plunger performs a synchronized forward and rotating movement. Cleverly arranged bores and channels in the cylinder and plunger control inspiration and expiration during each stroke of the plunger.

The extremely light weight and compact construction, in addition to the convenient rod clamp, allow the MidiVent ventilator to be positioned directly next to the animal. Typical setups with larger ventilators produce large tubing and instrument dead space volumes. These larger volumes introduce greater system compliance which can affect the accuracy with which the full tidal volume is introduced into the animal's lungs. With the MidiVent, the tidal volume error due to system compliance is reduced to 5 µl.

Tidal volume and respiration rate can be set exactly to the values required for mouse ventilation. The level of precision and control available to the investigator minimizes the danger of hyperventilation or hypoventilation.


The tidal volume can be varied continuously from 60 to 700 ul during operation without having to interrupt ventilation. The respiration rate is also continuously adjustable from 60 to 400 strokes/min. The expired air can be recovered at the collection port for sampling, recycling or for the generation of a positive end-expiratory pressure (PEEP). Room air or any non-explosive gas mixture can be used to feed the pump intake using the special connection tubing PY2 73-3077.


Components

The system is supplied with a 1.5 mm OD tracheal cannula and a 1.5 mm OD intubation cannula for the mice. For other size animals, additional intuubation or tracheal cannula sizes may be needed.


A multi-gas inlet adapter is available for the MidiVent so that alternate gas mixtures and nebulized substances are delivered to thr MidiVent inlet port at atmospheric pressure. The adapter provides ports for multiple selectable gas mixture (hypoxic, anesthetic...) and a port for the Aerosol Nebulizer.

Specifications

Ventilators

   73-4020  73-4119
Voltage Range 110 VAC 230 VAC
Number of Animals 1 1
Species Large mouse, small rat Large mouse, small rat
Control Modes Volume Volume
Gas Supply Room air or non-flammable mixed gas Room air or non-flammable mixed gas
Display  None None
IE Ratio,% 1.1 1.1
PEEP Provided via attachment of water column Provided via attachment of water column
Respiration Rate, Maximum, breaths/min 400 400
Respiration Rate, Minimum, breaths/min 60 60
Repiration Rate Note Continuously adjustable from 60 to 400 breaths/min Continuously adjustable from 60 to 400 breaths/min
Sigh Frequency None None
Sigh Pressure Not available Not available
Tidal Volume, Maximum, ml/stroke 700 700
Tidal Volume, Minimum, ml/stroke 60 60
Stroke Volume  Continuously adjustable from 60 to 700 µl Continuously adjustable from 60 to 700 µl
Weight Range, Maximum, g 100 100
Weight Range, Minimum, g 5 5
Dimensions, W x H x D, in (cm) 3.9 x 3.1 x 7.9 (10 x 8 x 20) 3.9 x 3.1 x 7.9 (10 x 8 x 20)
Net Weight, lb (kg) 2.2 (1) 2.2 (1)
AC Adapter Weight, lb (kg) 0.7 (0.3) 0.7 (0.3)
Certifications CE CE

HannahT. Nickles ,  Migle Sumkauskaite ,  Xin Wang ,  Ingmar Wegner ,  Michael Puderbach ,  Wolfgang M. Kuebler (2014 ) Mechanical ventilation causes airway distension with proinflammatory sequelae in mice Am J Physiolo Lung Cell Mol Physiol

DOCUMENT DESCRIPTION
Mini_Micro_MidiVent Manual.pdfMidiVent Ventilator (Type 849) User's Manual