CMA 12 Microdialysis Probes
- Optimized for CNS use
- Ideal for chronic implantation
- Available membrane: PAES, 20kDA MWCO or PES, 100 kDA MWCO
- Membrane lengths: 1, 2, 3 or 4 mm
- Membrane diameter: 0.5 mm
- Available metal free
The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals.
A semi-permeable membrane is glued between the tip of the inner steel cannnula and the outer steel shaft. The perfusion fluid enters the membrane space through two holes in the inner cannula and flows into the shaft to the outlet.
All metal parts are treated to prevent oxidation of labile compounds in the perfusate. The membrane is available in both 20 000 and 100 000 Daltons cut-off as standard. The inlet/outlet capillaries are mounted in a blue plastic body matched to the size of a corresponding CMA 12 guide cannula.
Once implanted, the probe sits tightly in the guide cannula´s capsule without the need for screwing or cementing. FEP tubing can be connected to the probe using tubing adaptors. The CMA 12 Microdialysis Probes are guaranteed for single use, however, with proper care, they may be reused several times. Complete instructions are included.
Specifications | CMA8010431 | CMA8010432 | CMA8010433 | CMA8010434 | CMA8309661 | CMA8309662 | CMA8309663 | CMA8309664 |
---|---|---|---|---|---|---|---|---|
Membrane Length | 1 mm | 2 mm | 3 mm | 4 mm | 1 mm | 2 mm | 3 mm | 4 mm |
Membrane O D | 0.5 mm | 0.5 mm | 0.5 mm | 0.5 mm | 0.5 mm | 0.5 mm | 0.5 mm | 0.5 mm |
Membrane Material | PAES | PAES | PAES | PAES | PES | PES | PES | PES |
Molecular Weight Cut-off | 20 kDA MWCO | 20 kDA MWCO | 20 kDA MWCO | 20 kDA MWCO | 100 kDA MWCO | 100 kDA MWCO | 100 kDA MWCO | 100 kDA MWCO |
Shaft Diameter | 0.64 mm | 0.64 mm | 0.64 mm | 0.64 mm | 0.64 mm | 0.64 mm | 0.64 mm | 0.64 mm |
Shaft Length Metric | 14 mm | 14 mm | 14 mm | 14 mm | 14 mm | 14 mm | 14 mm | 14 mm |
Intlet Internal Volume | negligible | negligible | negligible | negligible | negligible | negligible | negligible | negligible |
Outlet Internal Volume | 0.3 µL | 0.3 µL | 0.3 µL | 0.3 µL | 0.3 µ | 0.3 µ | 0.3 µ | 0.3 µ |
Model | Standard | Standard | Standard | Standard | Standard | Standard | Standard | Standard |
Gottås A, Ripel Å, Boix F, Vindenes V, Mørland J, Øiestad EL. (2015 ) Determination of dopamine concentrations in brain extracellular fluid using microdialysis with short sampling intervals, analyzed by ultra high performance liquid chromatography tandem mass spectrometry. J Pharmacol Toxicol Methods.