Flow Measurement Option for UP-100IH

TTFM-2

Flow measurement can be accomplished in a UP100-IH system iusing two methods.

  • Indirect measurement by controlling the pump sped of a roller pump (SCP controller)
  • Direct measurement with the ultrasound transit time technique (TTFM-2 module)

To ensure that your system is properly configured as a functional unit that meets your application needs, please complete our Checklist and then contact Technical Services at 800-547-6766 or via email at support@hbiosci.com before placing an order. In Europe, please call +49 7665 92000 or via email at sales@hugo-sachs.de. Upgrades can also be modified to meet your specific needs.

Item# Description U.S. List Price Quantity
73-2806 Servo Controller for Perfusion (SCP)
73-4617 Transit Time Flowmeter Module (TTFM-2)
73-4670 MA1.5 PRB Flow probe for TTFM-2 or TS420 Module
73-2993 Adapter for 73-4670 1.5RB Flow Probe for UP-100IH
73-2935 Holder for Block Flow Probes for UP-100 Systems
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Flow measurement can be accomplished in a UP100-IH system iusing two methods.

  • Indirect measurement by controlling the pump sped of a roller pump (SCP controller)
  • Direct measurement with the ultrasound transit time technique (TTFM-2 module)


Constant Pressure/Flow Control

The PLUGSYS Servo Controller Module (SCP) is used in combination with a roller pump to perfuse the heart in constant pressure mode. The SCP module calculates the coronary flow from the pump speed of the roller pump (indirect flow measurement). The PLUGSYS TAM-D module amplifies the measured perfusion pressure signal and outputs it to the data acquisition system. The roller pump is included in the UP-100IH Core System.

  • Allows operation in constant pressure or contant flow with simple switch
  • Additional measured signal/calculated parameters
    • Indirect coronary flow measurement
    • Calculation of coronary resistance

Features

  • Accurate control of perfusion pressure or flow, even at very low flow rates
  • Flexible perfusion circuit setup adjust to suit individual perfusion conditions


Direct  Flow Measurement with UltraSound Transit Time Flowmeter

The PLUGSYS TTFM-2 module provides real and accurate transit time flow measurement in ml/min for direct coronary flow measurement. In addition, species-specific flow probes and adapters are required.

Features & Benefits

  • Accurate ultrasonic transit time direct flow measurement
  • Unique integration of flow probe into perfusion path
  • Laminar flow lines improve accuracy of flow measurement
  • Thermal properties of Perspex adapter reduce temperature loss
  • Increased system flexibility by allowing the study of Myogene Autoregulation (Reactive Hyperemia)
  • Indirect flow measurement can typically follow increasing flow rates but often lags behind decreasing flow rates

Applications

  • Accurate coronary flow measurement on drug studies
  • Studies on coronary resistance changes (pre and post ischemia)
  • Myogene autoregulation (reactive hyperemia)

The table below specifies the flow probe and adapter to be used for the UP-100IH. It is extremely important to order the correct probe and adapter pair. If ordering online, please select carefully from the item listing or contact technical support for assistance.

Type of Measurement/Species Required Probe and Adapter
Direct Flow Measurement/ Rat, Guinea Pig, Juvenile Rabbit with UP-100IH
Application: Coronary flow measurement in retrograde Langendorff mode
73-4670 MA1.5PRB Flow Probe for TTFM-2 OR TS420 Module
73-2993 Adapter for 73-4670 1.5RB Flow Probe for UP-100IH
73-2935 Holder for Block Flow Probes for UP-100 Systems

 

Specifications73-2806
AccessoriesOperating Instructions, Screwdriver, Output Cable to Pump
Actual Value Input0 - 10 V via System Bus
Ambient ConditionsLaboratory Indoors
ConnectorDIN 41612, 96-pin VG
ConstructionPlug-in Module for a PLUGSYS
Control Gain1 - 50, Adjustable
Control Voltage0 - 10 V to Operate the Pump
Derivative Factor0.1 - 100, Adjustable
DescriptionServo Controller for Perfusion (SCP) Type 704
Digital IndicationRange -1999 to +1999, Selectable for Actual Value, Setpoint, or Control Output Signal
FunctionElectronic PID Controller for Physiological and Pharmacological Research
Integral Factor0.05 - 10, Adjustable
PLUGSYS Width*2 slot units
Power Supply5 V, 0.3 A from PLUGSYS
Recorder Output0 - 10 V, BNC Socket
Setpoint0 - 5 V, Adjustable
Weight (Metric)0.3 kg