Our Morris water maze is for spatial working memory studies. The circular pool is manufactured in polypropylene and stands on a support with 4 wheels for easier displacement. Panlab/Harvard Apparatus proposes a complete solution for water maze settings since the heater, the water circulation pump, the level controller and the electro valve for pool filling are containing in a unique control box. The level controller acts directly on the electro valve, turning it off when the liquid arrives to the corresponding height. The water temperature is thermostated between 22 and 32ºC depending on the environmental room temperature. For Morris Water Maze Test, 2 easily interchangeable platforms are supplied (80 and 110 mm) that can be located anywhere in the pool. For Radial Water Maze, a removable-floating eight radial-arm maze structure and associated platforms can be provided upon request.

Both Morris and Radial Water Mazes may be associated with the SMART Video- Tracking System for detection and analysis of animal displacements and behavior throughout the test.

Citations
Cho HJ et al. (2006) Repetitive dextromethorphan at adolescence affects water maze learning in femal rats. Int. J. Neurosci. 116(2): 91-101 (water maze, rat, Korea)
Zhang TY et al. (2006) Impairments in water maze learning of aged rats that received dextromethorphan repeatedly during adolescent period. Psychopharmacol. 5 in process (water maze, rat, South Korea)
Gimenez-Llort L et al. (2005) Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly. Synapse. 57(1): 8-16. (mouse, Spain, USA, Sweden)
Calza L et al. (2003) Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor. PNAS 100(12): 7325-7330. (rat, Italy)
Anisman H and McIntyre DC (2002) Conceptual, spacial, and cue learning in the morris water maze in fast or slow kindling rats: attention deficit comorbidity. J. Neurosci. 22(17):7809-7817. (rat, Canada)
Altafaj et al. (2001) Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome. Human Mol. Genetics 10(18): 1915-1923. (Morris water maze, mouse, Spain)
Wickman K et al. (2000) Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4. J. Neurosci. 20(15): 5608-5615. (mouse, USA)