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• Provides objective and accurate data
• The threshold value can be obtained in only one test, and in a highly reproducible
manner
• Elimination of the problems of filament standardization
• Stimulation of areas of equal size
• The end-point value is automatically recorded
The electronic model of Von Frey filament combines ease of use and rapidity for the determination of the mechanical sensitivity threshold in rodent.
The Von Frey filament is applied against the central edge of the animal hind paw. Paw withdrawal caused by the stimulation is registered as a response. The corresponding force applied is recorded by the system and displayed on the large backlighted screen of the Von Frey unit with a resolution of 0.1 grams.
Differently to the procedure using classical Von Frey filaments, the threshold value can be obtained in only one test, and in a highly reproducible manner. A foot switch is proved to carry out rapid hands-free experiments. RSIC software can be used to automatically record the results on a PC through a RS-232 port.
The electronic Von Frey is supplied with a COFRAC related calibration certificate (ISO 9000), and an EMC conformity agreement.
Citations
Chassaing C et al. (2006) Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers. Br. J. Clin. Pharmacol. 61(4): 389. (Human, France)
Benani A et al. (2003) Up-regulation of fatty acid metabolizing-enzymes mRNA in rat spinal cord during persistent peripheral local inflammation. Eur. J. Neurosci. 18: 1904-1914. (rats, France)
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Electronic Von Frey
