UP-100IH CORE SYSTEM, BASIC, 230V, 73-4385

UP-100IH CORE SYSTEM, BASIC, 230V, 73-4385

UP-100IH CORE SYSTEM, BASIC, 230V, 73-4385 If your chosen options require more than 10 Slot Units you will need to choose the UP-100IH Advanced system For a working unit, the core system requires the addition of a selection of one of the options UP-MOUSE or UP-RAT/GP.

Item# Description U.S. List Price Quantity
73-2070 HEART CHAMBER TO UP-100 SYSTEM (SIZE 3 RODENTS) INCL. HOLDER
73-0720 PARTS FOR ADAPTATION OF THE UP-100 FOR RETROGRADE LANGENDORFF HEART PERFUSION
73-0125 THERMOSTATIC CIRCULATOR E 103, BATH VOLUME 3 L, 230 V/50 Hz
73-2448 ISM 829/230V ROLLER PUMP REGLO ANALOGUE, 2 CHANNELS, 0.005 - 49.4 ML/MIN
73-2068 WINDKESSEL FOR ABSORPTION OF PULSATION CAUSED BY ROLLER PUMP
73-1521 PLUGSYS Case, Type 601
73-3862 APT300 Pressure Transducer for PLUGSYS Module
73-1793 Transducer Amplifier Module (TAM-D)
73-3869 Holder for APT300 Transducer, 8mm Rod, Length 75mm
73-0566 Plexiglass Block Clamp - for mounting 73-4337 Bar onto Lab Stand
73-0065 Transducer Amplifier Module (TAM-A)
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UP-100IH CORE SYSTEM, BASIC, 230V, 73-4385 The UP-100IH is the preferred system for compound screening that requires the basic measured parameters such as simple Left Ventricular Pressure (IsovolumetricLVP), ECG Lead II measurements, and temperature.Therefore the more common configuration of this system will be the UP-100IH Basic which allows the researcher to measure 2-3 parameters in addition to those that are included in the standard system (Aortic Pressure and LVP). Most researchers will also want to operate in a constant pressure perfusion mode and measure coronary flow, which is a simple addition to the basic system. The UP-100IH Advanced system allows up to the full range of available measured parameters beyond the basic system including direct coronary flow, ECG lead II, temperature measurement, and metabolic parameters (pH, pO2, pCO2). All UP-100IH systems can be used for constant pressure or constant flow perfusion of isolated hearts of mice, guineapigs, rats and newborn rabbits as long as the coronary flow is below 50 ml/min. Constant pressure perfusion is achieved by the optional addition of a controller (SCP) which modulates the flow generated by the perfusion pumpbased on a perfusion pressure feedback loop. The controller also provides an accurate, low-cost way to indirectly measure coronary flow. The system can be adapted for direct, real-time coronary flow measurement allowing the study of myogene autoregulation (reactive hyperemia) if required. Whether you are isolating cardiomyocytes following a physiology experiment or require occasional cardiomyocyte isolation in addition to the standard Langendorff assays, the Cell Isolation option to the UP-100IH will satisfy your requirements. Other useful add-ons include drug addition using a syringe pump and pacing. If perfusate containing albumin or erythrocytes is used, the oxygenation can be optimized with the addition of a fiber oxygenator. The complete system includes virtually everything you need to accomplish the basic Langendorff experiment, only requiring the addition of the appropriate species-specific package and the desired data acquisition system. Contact our expert technical team if you need assistance with system configuration, application support or custom design requests. If your chosen options require more than 10 Slot Units you will need to choose the UP-100IH Advanced system For a working unit, the core system requires the addition of a selection of one of the options UP-MOUSE or UP-RAT/GP.
Specifications73-244873-152173-386273-179373-386973-0065
Analog IndicationSpeed Control 0 - 5 V or 0 - 10 V and 0 - 20 mA respectivelyLine Cable, Screw driver for fitting Function Modules, Document Folder for Operating Instructions of Function Modules, 3 x BNC-BNC Output linesCETAM-A LED bar graph 20 LEDs (+13/-7) for visual check on the signal sensitivity approx. 1V/LED TAM-D 3 1/2-digit LED display75 mmTAM-A LED bar graph 20 LEDs (+13/-7) for visual check on the signal sensitivity approx. 1V/LED TAM-D 3 1/2-digit LED display
Bridge Balance1.0 bar (14.5 PSI)5.9 x 9.25 x 16.5 in3 mThrough 10-turn trimmer coarse adjustment and electronic autozero by push button (LED for error if autozero is not possible)8 mmThrough 10-turn trimmer coarse adjustment and electronic autozero by push button (LED for error if autozero is not possible)