Thermal Place Preference

Thermal Place Preference

For testing animal sensitivity to pain resulting from exposure to heat or cold.

  • Easily monitor thermal place preference and nociceptive thresholds
  • Unrestrained animals allows for maximum accuracy
  • Optional Automatic Detection Software eliminates the user subjectivity

Item# Description U.S. List Price Quantity
76-0475 Thermal place preference, 2 Cold hot plates delivered with a double perpex cage, without software
76-0476 Software for Thermal Place Preference, including camera, stand and USB cable
76-0785 Single casing unit with two plates dedicated to Thermal place preference
76-0912 Perpex cage for T2CT 2 mice 1 rat
76-0790 Kit to upgrade CHP to T2CT test
76-0911 Upgrade DHCP1 to V3
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This behavioral assay will allow monitoring of temperature preferences, nociceptive thresholds and investigate the role of a given gene or compound on these thresholds.

As advised by A. Moqrich and published in Moqrich et al (Science 2005, 307: 1468-72), this test allows researchers to work on unrestrained animals whom are free to choose their preferred position between two compartments at different temperatures.

Completely investigator-independent, the Two Temperature Choice Test elicits a nociceptive response from the subject. The obtained value is a temperature or temperature range indicating the sensitivity of the subject.

Using automatic detection software (optional), the user sets the temperature of each zone, defines a protocol of temperature changes or ramps, and starts the measurement process. Two animals can be observed simultaneously and independently, making the system remarkable efficient. The animals are video tracked and the software records their position vs. temperature and time.

When the optional automatic detection software is not used, temperatures must be defined manually and the user must measure the time and animal position.

Hache G, Guiard BP, Nguyen TH, Quesseveur G, Gardier AM, Peters D, Munro G, Coudoré F. (2015 ) Antinociceptive activity of the new triple reuptake inhibitor NS18283 in a mouse model of chemotherapy-induced neuropathic pain. Eur J Pain.