Series 2500 Small Animal Implantable Infusion Pump

Series 2500 Small Animal Implantable Infusion Pump

These Implantable Infusion Pumps have been designed to be accurate, versatile, and easy to use. The pumps are available in a range of reservoir sizes and with a wide range of flow rates to give you maximum flexibility in designing your studies. Some of the features of these pumps are not available on any other implantable pumps.

Item# Description U.S. List Price Quantity
72-4613 Series 2500 Continuous Flow Implantable Infusion Pump, 0.50 ml/day Flow Rate, 50 Day Flow Period, pkg. of 1
72-4612 Series 2500 Continuous Flow Implantable Infusion Pump, 0.75 ml/day Flow Rate, 33 Day Flow Period, pkg. of 1
72-4611 Series 2500 Continuous Flow Implantable Infusion Pump, 1.00 ml/day Flow Rate, 25 Day Flow Period, pkg. of 1
72-4610 Series 2500 Continuous Flow Implantable Infusion Pump, 1.50 ml/day Flow Rate, 17 Day Flow Period, pkg. of 1
72-4609 Series 2500 Continuous Flow Implantable Infusion Pump, 2.5 ml/day Flow Rate, 10 Day Flow Period, pkg. of 1
72-4608 Series 2500 Continuous Flow Implantable Infusion Pump, 4.25 ml/day Flow Rate, 6 Day Flow Period, pkg. of 1
72-4607 Series 2500 Continuous Flow Implantable Infusion Pump, 6.25 ml/day Flow Rate, 4 Day Flow Period, pkg. of 1
72-4606 Series 2500 Continuous Flow Implantable Infusion Pump, 10.0 ml/day Flow Rate, 2 Day Flow Period, pkg. of 1
72-4605 Series 2500 Continuous Flow Implantable Infusion Pump, 18.75 ml/day Flow Rate, 1 Day Flow Period, pkg. of 1
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• Completely Implantable
• Refillable
• Innovative suture band
• Wide range of reservoir volumes and flow rates
• Immune to ambient pressure changes
• Minimally sensitive to changes in ambient temperature
• Start drug delivery at any time
• Enables verification of amount of drug delivered
• Functions as either an implantable or portable external unit
• Crematable
These Implantable Infusion Pumps have been designed to be accurate, versatile, and easy to use. The pumps are available in a range of reservoir sizes and with a wide range of flow rates to give you maximum flexibility in designing your studies. Some of the features of these pumps are not available on any other implantable pumps.
The pump is filled by percutaneously accessing the pump’s refill septum. Once filled, the pump will continuously deliver fluid at a substantially constant, factory-set flow rate without any operator intervention until the pump is empty. Drug infusion can be stopped at any time by percutaneously emptying the pump. Drug delivery can be verified at any time by percutaneously accessing the pump reservoir and observing the volume of infusate remaining in the reservoir.
Each pump size is available with a variety of flow rates, offering from 1 to 50 days between refills. This provides maximum flexibility to match the pump to the requirements of the experiment. In addition, longer infusion periods or higher infusion rates can be achieved by sequentially refilling the pumps. Interruptions in therapy can likewise be achieved by using the pump to infuse a benign fluid (e.g., saline or the diluent), until the next phase of the experiment is to begin. At the end of the experiment, these pumps can be safely cremated.
These pumps are fully implanted devices, and they have no external connections. This enables animals to be co-housed and reduces the chance of infection. This feature, in conjunction with their unattended operation, reduces the need to monitor subjects, and can eliminate the need for repeated nighttime or weekend dosing.
These Implantable Pumps incorporate a pre-attached pump outlet catheter. These pumps have been used for the intravenous, intra-arterial, intraintestinal, intraspinal, intraventricular, intra-articular, intraperitoneal, intraocular delivery of a variety of fluids. Subcutaneous infusion is not recommended unless pilot studies verify an adequate drug absorption rate through the fibrous sheath that inevitably encapsulates the subcutaneous segment of the catheter within about two weeks of implantation.
Series 100
Series 100 pumps have 1 ml reservoir capacity. Although they can be used for animals of any size (>150 g) they are particularly appropriate for implantation in small animals, such as rats. The pumps are available in a range of nominal flow rates from 0.75 ml/24 hr (one day flow period) to 0.040 ml/24 hr (25 day flow period). In Series 100 pumps, the diaphragm functions as the fill septum, pressure source, and front wall of the pump reservoir. The pumps can be percutaneously refilled at least 100 times.
Series 2500
Series 2500 pumps have 25 ml reservoir volume and are designed for use on larger animals. They have been used successfully in animals as small as rabbits (>4 kg), and as large as livestock. The pumps are available in a range of nominal flow rates from 18.75 ml/24h (one day flow period) to 0.50 mL/24hr (50 day flow period). These pumps can be percutaneously refilled at least 500 times.
Note: Nominal flow rates are quoted for water at 37ºC with no backpressure. Infusate viscosity, temperature, and backpressure affect the pump flow rate.
Specifications72-461372-461272-461172-461072-460972-460872-460772-460672-4605
ApplicationsRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and largerRabbits (>4 kg) and larger
Delivered Volume25 ml25 ml25 ml25 ml25 ml25 ml25 ml25 ml25 ml
External Dimensions, Dia. x H, Metric75 x 25 mm75 x 25 mm75 x 25 mm75 x 25 mm75 x 25 mm75 x 25 mm75 x 25 mm75 x 25 mm75 x 25 mm
Flow Period50 days33 days25 days17 days10 days6 days4 days2 days1 day
Flow Rate Metric0.50 ml/day0.75 ml/day1.00 ml/day1.5 ml/day2.5 ml/day4.25 ml/day6.25 ml/day10.0 ml/day18.75 ml/day
Internal Filter Pore Size0.20.20.20.20.20.20.20.20.2
Power SourceDiaphragmDiaphragmDiaphragmDiaphragmDiaphragmDiaphragmDiaphragmDiaphragmDiaphragm
Refill Septum: Compatible Needles (max size)22 G22 G22 G22 G22 G22 G22 G22 G22 G
Refill Septum: Needle TypeNon-coringNon-coringNon-coringNon-coringNon-coringNon-coringNon-coringNon-coringNon-coring
Refill Septum: Puncture Life (min punctures)500500500500500500500500500
Reservoir Pressure English8 Psi8 Psi8 Psi8 Psi8 Psi8 Psi8 Psi8 Psi8 Psi
Reservoir Pressure Metric0.55 Bar0.55 Bar0.55 Bar0.55 Bar0.55 Bar0.55 Bar0.55 Bar0.55 Bar0.55 Bar
Weight (Empty)120 g120 g120 g120 g120 g120 g120 g120 g120 g