Remote Infuse/Withdraw PHD ULTRA™ Syringe Pumps

Remote Infuse/Withdraw PHD ULTRA™ Syringe Pumps

The PHD ULTRA™ is the solution for your most demanding fluidics applications. This pump represents the latest technology in syringe pumps and was developed utilizing the feedback of the world's largest populations of syringe pump users.

Remote Pump Model

The PHD ULTRA™ Remote Pumps consist of a control unit and syringe pumping mechanism all connected via a 30 foot RS-485 (IEEE-1394) cable. This makes the pump ideal for use in hazardous environments where the researcher is safer distanced from the material being pumped or for applications where you need to have the pumping mechanism inside an incubator. Every version of the PHD ULTRA™ is available in a remote model.

The PHD ULTRA™ will change the way you think about syringe pumps. There are three major areas which make the PHD ULTRA™ the new standard for syringe pumps:

1. Superior mechanical drive mechanism and syringe holding mechanics to achieve the highest performance of any syringe pump

2. Integrated EZ PRO Software and user interface allow easy programming of methods from simple to complex, all without the use of a PC 
    - Preprogrammed methods for simple to complex operations that allow you to be up and running with the push of a button
    - LCD, high resolution color touch screen for powerful functionality, yet easy to use

3. Multiple levels of versatility
    a. Configurations: push-pull, standard, remote, high pressure, multi racks
    b. Connectivity: RS-232 and USB for PC; RS-485 for pump to pump daisy chain

Please follow this link for syringe options.

Please follow this link for tubing and connector options.

Item# Description U.S. List Price Quantity
70-3306 PHD ULTRA™ Remote Syringe Pump Infuse/Withdraw Standard
70-3307 PHD ULTRA™ Remote Syringe Pump Infuse/Withdraw Programmable
70-3308 PHD ULTRA™ Remote Syringe Pump with Push/Pull Mechanism
70-3309 PHD ULTRA™ Remote Syringe Pump Programmable with Push/Pull Mechanism
70-3020A PHD ULTRA™ 6x10 MultiRack - when purchased with Pump
70-3021A PHD ULTRA™ 4x140 MultiRack - when purchased with Pump
70-3022A PHD ULTRA™ MicroDialysis MultiRack - when purchased with Pump
70-3030 PHD ULTRA™ RS-232 RJ-11 Connectors Option (If needed, must be purchased at the same time as the Ultra Pump)
70-3033 PHD ULTRA™ Analog Control Input Option (If needed, must be purchased at the same time as the PHD ULTRA™ Programmable Pump)
70-3034 PHD ULTRA™ Internal Fan Option (Required if external operating ambient is >35°C. If needed, fan must be purchased at the same time as the PHD ULTRA™ Pump)
Login for U.S. Pricing

Features:
• Superior drive mechanism for unmatched smooth flow, accuracy and precision
• From picoliter to 216 ml/min flow rates
• Advanced programming for true multi methods without a PC
• Quick start methods
• Alpha/numeric keyboard without a PC
• Real and relative time clocks
• Icon operation
• Color LCD touch screen
• Up-front control knobs for ease of operation
• Vertical or horizontal orientation
• Adjustable linear force to 75 lbs across the entire flow range
• Daisy chain
• Remote configuration available
• CE, ETL(UL, CSA), WEEE, EU RoHS + CB Scheme
• 2 year warranty

Applications:
• Nanofluidics
• Drug/Nutritional infusions
• Electro-spinning
• Reaction chamber addition
• Mass Spec calibration
• Feeding cells
• Low pressure chromatography
• Continuous flow
• Flow programming
• Gradients
• % composition step changes
• Large flow deliveries
• I/O interactive experiments

 The PHD ULTRA™ is the solution for your most demanding fluidics applications. This pump represents the latest technology in syringe pumps and was developed utilizing the feedback of the world's largest populations of syringe pump users.

Remote Pump Model

The PHD ULTRA™ Remote Pumps consist of a control unit and syringe pumping mechanism all connected via a 30 foot RS-485 (IEEE-1394) cable. This makes the pump ideal for use in hazardous environments where the researcher is safer distanced from the material being pumped or for applications where you need to have the pumping mechanism inside an incubator. Every version of the PHD ULTRA™ is available in a remote model.

The PHD ULTRA™ will change the way you think about syringe pumps. There are three major areas which make the PHD ULTRA™ the new standard for syringe pumps:

1. Superior mechanical drive mechanism and syringe holding mechanics to achieve the highest performance of any syringe pump

2. EZ PRO Software and user interface allow easy programming of methods from simple to complex, all without the use of a PC (I/W and I/W Programmable models only)
- Preprogrammed methods for simple to complex operations that allow you to be up and running with the push of a button (I/W Programmable models only)
- LCD, high resolution color touch screen for powerful functionality, yet easy to use

3. Multiple levels of versatility
a. Configurations: push-pull, standard, remote, high pressure, multi racks
b. Connectivity: RS 232 and USB for PC; RS 485 for daisy chain

Harvard Apparatus introduces the next generation of syringe pumps, the PHD ULTRA™ for the most demanding applications.

Since 1901 Harvard Apparatus has been supporting bioresearch fluidics requirements with the culmination being the introduction of the first commercial syringe pump for bioresearch in 1956. Since 1956, over 70,000 satisfied syringe pump users around the world have made Harvard Apparatus syringe pumps the worlds #1 choice.

The PHD ULTRA™ Syringe Pump series is a family of high-accuracy, microliter- and milliliter-compatible pumps designed for versatile technical use including mass spectroscopy, calibration, drug and nutritional infusions, microdialysis, dispensing, chromatography and LC/HPLC.

Highest Accuracy and Precision
The PHD ULTRA™ syringe pump family has a fluidics drive mechanism which assures ease of use and high performance, for smoother, more accurate flow rates than any other syringe pump. Flow rates are accurate within 0.25% and reproducibility within 0.05%. A microprocessor-controlled, small step angle stepping motor drives a lead screw and pusher block. Advanced micro-stepping techniques are employed to further reduce the step angle to eliminate flow pulsation.

Advanced Programming Features:
• Flow Programming - Change the flow with time, volume or a triggered event as many times as you like
• Bolus - Inject a drug (or drugs) in a high quantity at once. The bolus injection can be made in time or volume.
• Concentration Delivery - Calibrate flow in concentration units of mg/kg easily so flow is calibrated to concentration of drug and animal weight.
• Gradients
• % ratio - up to three solvents
• I/O — dedicated and user defined I/O
• Pulsed Flow- so you can program the pulse easily

Widest Flow Rate Range
This pump is engineered to provide flow accuracy within 0.25% and reproducibility within 0.05%. Single or multi syringes from 0.5 µl to 140 ml pump at a range of 0.0001 µl/hr to 216 ml/min.

Maximum Experimental Versatility
The PHD ULTRA™ features true Multi-Pump Operation. The pump can be oriented vertically or horizontally for optimum experimental connectivity. This pump comes standard to hold 2 syringes, but can be purchase with 3 other syringe racks: 6 to 10 syringe rack, 4 x 140ml syringe rack and 4 x microliter syringe rack.

Easy-to-Use Interface
The PHD ULTRA™ color LCD touch screen graphic interface is divided into three basic areas: Operations Display, Message Area, and Navigation. This configuration allows you to easily move through all menu selections and data entry by gently touching the onscreen buttons with a finger or the tip of a soft, non-sharp object such as a pencil eraser.

The Methods Main or Quick Start screens are the primary home for the applications. From those screens you access all the commands needed to operate the PHD ULTRA™, as well as the main system settings.

The Message Area of the touch screen is used to display helpful instructions for the currently displayed screen. It is also used to display error or warning messages to indicate problem conditions in a Method or error conditions during pump operation.

The software is organized into three main Navigational branches, the quick start operations, preloaded/user-defined Methods, and systems settings. You can control operations directly with the touch screen or remotely from an independent computer or device via the external I/O interface.

Program Description
To operate the PHD ULTRA™, the user defines all the required parameters for infusing or withdrawing liquids through a Pump Control Method. The basic operation is a simple 4-step procedure:

1. Select a method
2. Enter operating parameters
3. Preview your method
4. Run your method

Applications
• Animal Infusions or Withdrawals - The PHD ULTRA™ will control the delivery of varying % of nutrients or drugs infused into animals, flush lines using catheters, needles, cannulae or microdialysis.
• Proportioning and Delivering of Mixtures - Mixing gradients or proportions with independent control of two liquids.
• Aerosol for Coating - The pump at high pressure can create an aerosol for the delivery of coating materials such as pharmaceutical tablets and aerosol studies.
• Delivery to Mass Spectroscopy - The delivery of fluids to the MS for calibration, matrix addition or ESI sample.
• Compensating Flows - The continuous infusion and simultaneous withdrawal of liquids for cell cultures or perfusion chambers.
• Dispensers/Injectors — Adhesives, Cell injection, MRI Dyes, Activators/Enzymes, Flow injection, Microreaction vessels, or Stereotaxic delivery.

Advanced GLP Documentation Features:
• Experiment parameter download information to PC
• Alpha/numeric capability

Syringe Racks
The PHD ULTRA™ is offered with a variety of syringe racks to meet your specific application.

Upgrade
We offer pumps that can be upgraded. If you buy an infuse/withdraw pump and later decide you want programmability you can upgrade it. You pay a lot less than buying a whole new pump. (pump must be returned to the factory for all upgrades)

Accessories
A full range of accessories are compatible with the PHD ULTRA™ including syringe heaters, connectors, tubing, syringes and more.


Please follow this link for syringe options.

Please follow this link for tubing and connector options.

Specifications70-330670-330770-330870-3309
Accuracy±0.25%±0.25%±0.25%±0.25%
ClassificationClass IClass IClass IClass I
Dimensions Control Box LxDxH in (cm)12 x 8.5 x 4.25 (30.48 x 21.59 x 10.80)12 x 8.5 x 4.25 (30.48 x 21.59 x 10.80)12 x 8.5 x 4.25 (30.48 x 21.59 x 10.80)12 x 8.5 x 4.25 (30.48 x 21.59 x 10.80)
Dimensions Remote Box LxDxH in (cm)11.0 x 5.3 x 6.5 (27.94 x 13.46 x 16.51)11.0 x 5.3 x 6.5 (27.94 x 13.46 x 16.51)11.0 x 5.3 x 6.5 (27.94 x 13.46 x 16.51)11.0 x 5.3 x 6.5 (27.94 x 13.46 x 16.51)
Display4.3" WQVGA TFT Color Display with Touchpad4.3" WQVGA TFT Color Display with Touchpad4.3" WQVGA TFT Color Display with Touchpad4.3" WQVGA TFT Color Display with Touchpad
Drive Motor0.9° Stepper Motor0.9° Stepper Motor0.9° Stepper Motor0.9° Stepper Motor
Environmental Humidity20% to 80% RH, non condensing20% to 80% RH, non condensing20% to 80% RH, non condensing20% to 80% RH, non condensing
Environmental Operating Temperature English40°F to 104°F40°F to 104°F40°F to 104°F40°F to 104°F
Environmental Operating Temperature Metric4°C to 40°C4°C to 40°C4°C to 40°C4°C to 40°C
Environmental Storage Temperatue English14°F to 158°F14°F to 158°F14°F to 158°F14°F to 158°F
Environmental Storage Temperatue Metric-10°C to 70°C-10°C to 70°C-10°C to 70°C-10°C to 70°C
Flow Rate Maximum216 ml/min using 140 ml syringe216 ml/min using 140 ml syringe216 ml/min using 140 ml syringe216 ml/min using 140 ml syringe
Flow Rate Minimum1.5 pl/min using 0.5 µl syringe1.5 pl/min using 0.5 µl syringe1.5 pl/min using 0.5 µl syringe1.5 pl/min using 0.5 µl syringe
I/O & TTL Connectors15 pin D-Sub Connector15 pin D-Sub Connector15 pin D-Sub Connector15 pin D-Sub Connector
Input Power50 W, 0.5 A fuse50 W, 0.5 A fuse50 W, 0.5 A fuse50 W, 0.5 A fuse
Installation CategoryIIIIIIII
Max Linear Force75 lbs @ 100% Force Selection75 lbs @ 100% Force Selection75 lbs @ 100% Force Selection75 lbs @ 100% Force Selection
Mode of OperationContinuousContinuousContinuousContinuous
Motor Drive ControlMicroprocessor with 1/16 microsteppingMicroprocessor with 1/16 microsteppingMicroprocessor with 1/16 microsteppingMicroprocessor with 1/16 microstepping
Net Weight English13.4 lb13.4 lb13.4 lb13.4 lb
Net Weight Metric6.1 kg6.1 kg6.1 kg6.1 kg
No of Syringes2244
Non Volatile MemoryStorage of all settingsStorage of all settingsStorage of all settingsStorage of all settings
Number of Microsteps per one rev of Lead Screw12,80012,80012,80012,800
Pollution Degree1111
Pump ConfigurationRemoteRemoteRemoteRemote
Pump FunctionInfuse/WithdrawInfuse/Withdraw, ProgrammablePush/PullPush/Pull, Programmable
Pusher Travel Rate Maximum190.8 mm/min190.8 mm/min190.8 mm/min190.8 mm/min
Pusher Travel Rate Minimum0.18 µm/min0.18 µm/min0.18 µm/min0.18 µm/min
RS 232 Connectors9 pin D-Sub Connector9 pin D-Sub Connector9 pin D-Sub Connector9 pin D-Sub Connector
Regulatory CertificationsCE, ETL(UL, CSA), WEEE, EU RoHS + CB SchemeCE, ETL(UL, CSA), WEEE, EU RoHS + CB SchemeCE, ETL(UL, CSA), WEEE, EU RoHS + CB SchemeCE, ETL(UL, CSA), WEEE, EU RoHS + CB Scheme
Reproducibility±0.05%±0.05%±0.05%±0.05%
Step Rate Maximum26 µsec/µstep26 µsec/µstep26 µsec/µstep26 µsec/µstep
Step Rate Minimum27.5 sec/µstep27.5 sec/µstep27.5 sec/µstep27.5 sec/µstep
Syringe Rack TypeStandard RackStandard RackStandard RackStandard Rack
Syringe Size Maximum140 ml140 ml140 ml140 ml
Syringe Size Minimum0.5 µl0.5 µl0.5 µl0.5 µl
USB ConnectorsType BType BType BType B
Voltage Range100-240 VAC, 50/60 Hz100-240 VAC, 50/60 Hz100-240 VAC, 50/60 Hz100-240 VAC, 50/60 Hz

Xizhong Cui, PhD; Yvonne Fitz, BS; Yan Li, MD; Ping Qiu, Ph.D; Steve Solomon, Ph D; Mariam Al-Hamad, BS & Peter Q. Eichacker, MD (2013 ) Pilot Investigation Of A Multi-Channel Automated Drug Delivery System For Blood Pressure Regulated Vasopressor Administration In A Rat Model ATS Journals

Amber L. Alhadeff , Matthew R. Hayes , Harvey J. Grill (2014 ) Leptin receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake American Journal of Physiology

Vivek Sharma, Simon J. Haward, James Serdy, Bavand Keshavarz, Asa Soderlund, Phil Threlfall-Holmes & Gareth H. McKinley (2015 ) The rheology of aqueous solutions of ethyl hydroxy-ethyl cellulose (EHEC) and its hydrophobically modified analogue (hmEHEC): extensional flow response in capillary break-up, jetting (ROJER) and in a cross-slot extensional rheometer Royal Society of Chemistry

Amber L. Alhadeff, Laura E. Rupprecht, and Matthew R. Hayes (2011 ) GLP-1 Neurons in the Nucleus of the Solitary Tract Project Directly to the Ventral Tegmental Area and Nucleus Accumbens to Control for Food Intake Endocrine Society

Ryan W. Mutharda & Scott L. Diamond (2013 ) Side view thrombosis microfluidic device with controllable wall shear rate and transthrombus pressure gradient Lab On A Chip

G. L. Scaglione, S. Lancellotti1, M. Papi1, M. De Spirito, A. Maiorana, L. Baronciani, M. T. Pagliari, A. Arcovito, E. Di Stasio, F. Peyvandi, R. De Cristofaro (2013 ) The type 2B p.R1306W natural mutation of von Willebrand factor dramatically enhances the multimer sensitivity to shear stress The Journal of Thrombosis and Haemostasis

Youri Gendelb, Oana Davidb & Matthias Wesslinga (2013 ) Microtubes made of carbon nanotubes Science Direct

Jidong Wang, Wenwen Chen, Jiashu Sun, Chao Liu, Qifang Yin, Lu Zhang, Yunlei Xianyu, Xinghua Shi, Guoqing Hu & Xingyu Jiang (2014 ) A microfluidic tubing method and its application for controlled synthesis of polymeric nanoparticles Lab On A Chip

J. D. Welsh, T. V. Colace, R. W. Muthard, T. J. Stalker, L. F. Brass & S. L. Diamond (2012 ) Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse The Journal of Thrombosis and Haemostasis

Dominika Ogończyk, Mateusz Gocyla, Marcin Opallo (2014 ) Electrochemical response of catalytic nanoparticles in Flow Injection Analysis system Science Direct

James O. Hardin, Thomas J. Ober, Alexander D. Valentine & Jennifer A. Lewis (2015 ) Microfluidic Printheads for Multimaterial 3D Printing of Viscoelastic Inks Advanced Materials

Nan Li, Miguel F. Diaz, Pamela L. Wenzel Ph.D. (2014 ) Application of Fluid Mechanical Force to Embryonic Sources of Hemogenic Endothelium and Hematopoietic Stem Cells Methods in Molecular Biology

Wahyudionoa, Kanako Murakamia, Siti Machmudahb, Mitsuru Sasakia & Motonobu Gotob (2011 ) Production of nanofibers by electrospinning under pressurized CO2 High Pressure Research: An International Journal

Iulia - Rodica Damian, Nicoleta Octavia Tănase, Ștefan - Mugur Simionescu, Mona Mihăilescu (2015 ) Vortex Rings - Experiments and Numerical Simulations Mathematical Modelling in Civil Engineering

C. Liua, J.D. Yeagera & K.J. Ramosa (2015 ) Bonding energy of Sylgard on fused quartz: an experimental investigation Philosophical Magazine

Stephen G. Newman , Kyoungmi Lee , Jianghuai Cai , Lu Yang , William H. Green , and Klavs F. Jensen (2014 ) Continuous Thermal Oxidation of Alkenes with Nitrous Oxide in a Packed Bed Reactor Industrial & Engineering Chemisrty Research

Jinyoung Baekm Dr. Peter M. Allen, Prof. Moungi G. Bawendi & Prof. Klavs F. Jensen (2010 ) Investigation of Indium Phosphide Nanocrystal Synthesis Using a High-Temperature and High-Pressure Continuous Flow Microreactor Angwandte Chemie

I. R. G. Ogilvie, V. J. Siebe, M. C. Mowlem, and H. Morgan (2011 ) Temporal Optimization of Microfluidic Colorimetric Sensors by Use of Multiplexed Stop-Flow Architecture Analytical Chemistry

Isabella Pallotta, Ph.D., Michael Lovett, Ph.D., David L. Kaplan, Ph.D. & Alessandra Balduini, M.D. (2011 ) Three-Dimensional System for the In Vitro Study of Megakaryocytes and Functional Platelet Production Using Silk-Based Vascular Tubes Tissue Engineering

Laurent Pellegatti and Stephen L. Buchwald (2012 ) Continuous-Flow Preparation and Use of β-Chloro Enals Using the Vilsmeier Reagent Organic Process Research & Development

DOCUMENT DESCRIPTION
PHD ULTRA Manual-70-3xxx_5419-002REV1.0.pdfPHD ULTRA Syringe Pump Series Manual
PHD ULTRA Quickstart_5419-001REVE.pdfPHD ULTRA Touchscreen Button Reference