Plethysmometer (Panlab)

Plethysmometer (Panlab)

The Digital Water Plethysmometer is designed to provide a highly useful tool in the measurement of small volume changes. This test is typically used to follow the evolution of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or anti-oedema properties of pharmacological substances.

  • Automatic zero adjustment
  • “Check solution” status button
  • Foot-switch control
  • New optional Data Transfer software SEDACOM 2.0

Item# Description U.S. List Price Quantity
76-0220 (LE7500) Digital Water Plethysmometer (cell, calibrator and software provided separately)
76-0221 (LE7504) 1 ml Cell with Electrode
76-0223 (LE7503) 3 ml Cell with Electrode
76-0222 (LE7505) 5 ml Cell with Electrode
76-0406 (SEDACOMV2.0) SEDACOM Software V2.0
76-0608 (CONRS232USB) RS-232/USB Adapter for the SEDACOM software
76-0114 (LE7000) Thermal Printer
76-0225 (LE75301) Replacement - 1 ml Calibrator for Plethysmometer
76-0226 (LE75303) Replacement - 3 ml Calibrator for Plethysmometer
76-0436 (LE75305) Replacement - 5 ml Calibrator for Plethysmometer
76-0224 (LE7506) Replacement- Platinum Electrode
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The Digital Water Plethysmometer is designed to provide a highly useful tool in the measurement of small volume changes. This test is typically used to follow the evolution of the inflammatory response experimentally induced in rodents and to screen potential anti-inflammatory or anti-oedema properties of pharmacological substances.

Basically, the volume transducer is formed by two Perspex tubes interconnected and filled with a conductive solution and a platinum electrode for each chamber. All the system is supported by a stand (included) that can be placed over the control unit.

The water displacement produced by the immersion of the animal paw in the measuring tube is reflected into the second tube, inducing a change in the conductance between the two platinum electrodes. The Plethysmometer Control Unit detects the conductance changes and generates an output signal to the digital display indicating the volume displacement measured (0.01 ml resolution). The current value remains in the digital display until a new trial starts. The Control Unit is automatically zeroed between successive readings, thus making intermediate adjustments unnecessary.

A remote foot-switch allowing rapid hands-free experiments can be used to set control the end point of the measurement.

The optional SeDacom software (new version 2.0 available) can be used and represents an easy and convenient way to visualize and export the data on a computer for further analysis.
Specifications76-022176-022376-0222
SpecieMouseRatRat
Control Unit Dimensions (WxDxH)280 x 280 x 110 cm280 x 280 x 110 cm280 x 280 x 110 cm
Stimulation Unit Dimensions (WxDxH) 230 x 220 x 300 cm 230 x 220 x 300 cm 230 x 220 x 300 cm
Power Supply220/110V, 50/60Hz220/110V, 50/60Hz220/110V, 50/60Hz
Resolution3 digits; 0.01 steps3 digits; 0.01 steps3 digits; 0.01 steps
Cell Volume1 ml3 ml5 ml
Cell Inner Diameter12 mm20 mm24 mm

Silva RO, Damasceno SR, Brito TV, Dias JM, Fontenele AM, Braúna IS, Júnior JS, Maciel JS, de Paula RC, Ribeiro RA, Souza MH, Freitas AL, Medeiros JV, Silva DC, Barbosa AL. (2015 ) Polysaccharide fraction isolated from Passiflora edulis inhibits the inflammatory response and the oxidative stress in mice. J Pharm Pharmacol.

DOCUMENT DESCRIPTION
LE7500_Plethysmometer_EN.pdfPlethysmometer - English