Syringe Pumps NanoCool™ Injector NanoCool HandHeld or Stereotaxic Mounted Injector SYRINGE PUMPS NanoCool™ Injector Control Unit Footswitch KEY FEATURES 18ºC for optimal cell viability on any delivery syringe and Eppendorf 20% Increase in Survivability, 76% Lower O2 Consumption Rate at 18ºC vs. 37ºC Flow ramping to reduce injection site blowback Programmed methods for automatic recall of entire cell delivery system. Up to 100 methods stored for recall 2 year warranty High accuracy delivery between 3.66 pl/min to 1.91 ml/min Preprogrammed bolus injection mode, just specify injection size and time of dispense Footswitch activation keeps hands free Temperature Effect on O2 Consumption by Organ Cell Type Organ Kidney Liver Heart Brain Muscle Skin Temperature 37 to 18 37 to 18 37 to 18 37 to 18 37 to 18) 37 to 18 Oxygen Consumption 3.7 to 0.9 3.0 to 0.6 2.4 to 0.7 1.9 to 0.4 0.8 to 0.2 0.4 to 0.1 Change in O2 Consumption 2.8 2.4 1.7 1.5 0.6 0.3 % Change 75.7 80 70.8 78.9 75 75 NanoCool™ Cell Delivery System IR Temperature Image NanoCool at 18°C When injecting stem cells viability of cells can be a major issue. The injection system and sample vortex holder are held at 18ºC. The cell delivery is totally integrated in it operation through the NanoCool’s microprocessor system: power, temperature injection volumes and flow ramping are all controlled by the NanoCool’s program. Keeping the cells at 18ºC instead of 37ºC reduces O2 consumption of cells by an average of 76%. The chart to the right shows the different organ utilization curves. NanoCool™ Injector Specifications ACCURACY REPRODUCIBILITY SYRINGES (MIN./MAX.) FLOW RATE: Minimum Maximum INJECTOR HEAD/ACTUATOR, LxHxW 3.66 pl/min 1.91 ml/min 20.3 x 5.1 x 5.1 cm (8 x 2 x 2 in) ±0.5% ±0.05% 50 µl / 500 µl Order # PC4 88-1050 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 Product NanoCool™ Injector www.harvardapparatus.com fax 508.429.5732 29