McIlwain Tissue Slicers

McIlwain Tissue Slicers

This tissue chopper has been designed to prepare pieces of tissue for metabolic experiments. It is especially suited to small and irregular specimens available at biopsy or from small organs. It causes much less disturbance of the cell structure than homogenizers or blenders, and to be applicable to fragments which would be difficult or impossible to cut by ordinary methods. It has been applied to liver, kidney and various parts of the central nervous system.

Item# Description U.S. List Price Quantity
69-1013 Blade Holder
69-1017 Spanner
69-1016 Cutting Table Clips
69-1015 Replacement Cutting Table
69-1014 Cutting Table Disk (PVC, Darvik), pkg. of 10
69-1012 Cutting Blades, pkg. of 10
69-1010 McIlwain Mechanical Tissue Chopper, 115 V, 60 Hz
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• Less disturbance of cell structure than homogenizers or blenders


• Slices up to 1 mm thick and cubes or prisms up to 1 mm cross section


• To prepare tissues for metabolic experiments
This tissue chopper has been designed to prepare pieces of tissue for metabolic experiments. It is especially suited to small and irregular specimens available at biopsy or from small organs. It causes much less disturbance of the cell structure than homogenizers or blenders, and to be applicable to fragments which would be difficult or impossible to cut by ordinary methods. It has been applied to liver, kidney and various parts of the central nervous system.


This tissue chopper will produce slices up to 1 mm thick and cubes or prisms up to 1 mm in cross section can be prepared with the chopper in 30 seconds. The stepless variation of slice thickness from zero to the maximum is controlled by an index clutch in conjunction with a micrometer head, the latter being calibrated in microns.


The action of the machine is as follows: a circular stainless steel table, on which the specimen is placed, is traversed automatically and at a speed which can be varied, from left to right of the machine. At the same time a chopping arm carrying a blade is raised and dropped by its own weight and the tension of a spring, at speeds varying from zero to a maximum of 200 strokes per minute. As the table carrying the tissue passes under the blade it is chopped into the required slices. If prisms are required the table is returned to the left hand side of the machine, turned through 45 degrees, and the process repeated. Cubes are formed by rotating the table 90 degrees. A safety limit switch is provided to prevent the machine overrunning and a quick return mechanism is fitted for the return of the table. All parts coming into contact with the tissues are of stainless steel. Finish is in white powder coat. Operation


1. Positioning Blade: Filter papers are placed on the circular table and a blade loosely clamped to the arm. The arm is brought to rest on the stop rod by rotating the handwheel on the motor shaft and the blade pressed down with the fingers. The blade is then securely clamped in this position. The machine is switched on and it will probably cut the top filter paper. This is removed and the machine is ready to take a specimen.


2. Slice Thickness: The thickness of slice is adjusted by means of the micrometer head. The maximum thickness is 1 mm. Each division on the thimble is 1 µ. Each small division on the barrel is 25 µ.


3. Force on Blade: The force on the cutting arm can be adjusted by the front knob. To increase tension turn in clockwise direction.


4. Cutting: Pull out the carriage release knob and slide the table to the left of the machine. Place the specimen on the centre of the table and with the rheostat in the slow position switch on the bottom switch. Increase the rheostat until the desired speed has been attained. After the tissue has been cut into slices it may, if desired, be turned 90 degrees and formed into cubes, after passing under the cutting arm again. The machine automatically switches itself off at the end of its travel. When this limit switch is used it must be reset by means of the top button. The cutting arm is made of stainless steel and may be removed for the purpose of sterilization.


5. Plastic Cushion: This machine is now fitted with a plastic cushion held in place by two spring clips on the table. The specimen may be fixed to a suitable filter paper by means of a fixative such as agar, which in turn is cemented to the cushion, and then inserted under the springs. This arrangement holds the specimen firmly down and prevents it sticking to the blade during chopping.
Specifications69-101369-101769-101669-101569-101469-101269-1010
Blade Speed      Zero to 200
Certifications      CE
Depth English      5.9
Depth Metric      15
Height English      11.8
Height Metric      30
Maximum Blade Height      ~1
Power      115 V, 60 Hz
Slice Thickness Settings      1 mm max. with 1 mm scale resolution
Weight English      13.9
Weight Metric      6.3
Width English      11
Width Metric      28.0