In-line Heater/Cooler (SC-20)

In-line Heater/Cooler (SC-20)

This dual in-line solution heater/cooler extends the temperature range for controlled perfusion studies of both coverslip mounted cells and anchored tissue thin slices.

  • Heats or cools perfusate*
  • Compatible with all Warner Series 20 chambers
  • Requires a CL-100 Bipolar Temperature Controller
  • Versatile and simple to use thermal control device

*Users should recall that saturation levels for many ionic compounds decrease at lower temperatures.

Item# Description U.S. List Price Quantity
64-0353 SC-20 Solution In-line Heater/Cooler Two Line
64-0352 CL-100 Bipolar Temperature Controller
64-1922 (LCS-1) Liquid Cooling System
64-0354 PHC Series Heater/Cooler Jackets for RC-22/22C/24N, RC-26/26G/26GLP/26Z, RC-27/27N/27NE, RC-28, RC-27L, RC-29 Chamber Models
64-0355 PHC Series Heater/Cooler Jackets for RC-22/22C/24N, RC-26/26G/26GLP/26Z Chamber Models
64-0356 PHC Series Heater/Cooler Jackets for RC-27/27N/27NE Chamber Models
64-1556 (SHH-2) Holder for SC-20 solution heater/cooler
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In-line solution heating has proven to be one of the most effective methods of maintaining the temperature of perfusion solutions. The SC-20 Dual In-line Solution Heater/Cooler utilizes Peltier thermoelectric technology to regulate temperature both above and below ambient levels.

The SC-20 is designed to thermally regulate one or two solutions at the same temperature. Temperature regulation is provided by the CL-100 or CL-200A Bipolar Temperature controller. Solution temperatures can be maintained at 0°C at flow rates of 2 mL/min., 5°C at 5 mL/min., or as high as 50°C at 5 mL/min.

An integral water jacket is used to remove excess heat from the SC-20. Running water from a tap or large reservoir can be used as a source. Flow rates as low as 1 gallon per hour is sufficient to maintain effecient cooling.

The SC-20 can be used with either one or two discrete perfusate solutions, or with a solution/gas combination. When coupled with a PHC Series Imaging Chamber Heater/Cooler Jacket, the SC-20 provides an effective means of temperature control in the chamber, even under slow-flow conditions.

Each heater/cooler is supplied with a TA-29 Thermistor Cable Assembly for monitoring the bath temperature.

Specifications
Minimum Temperature 0°C at 2 mL/min
maximum flow
Maximum Temperature 50°C
Maximum Flow
Rate at 5°C
5 mL/min
Accuracy ± 0.1°C
Internal Dead Volume 330 µL
Controller Model CL-100
Bipolar Controller
Perfusion Lines Type 316 Stainless Steel
0.032 ID x 0.062 OD
Water Jacket Ports Type 316 Stainless Steel
0.12 ID x 0.147 OD
Body Physical
Dimensions
21 mm diameter x
165 mm long
Weight 109 grams
Cable Length 1.9 meters
Connector Type 15 pin Male D
Warranty 1 year


Infrared Image

  QE-1HC Quick Exchange Heated / Cooled platform with
  SC-20: cooling with perfusion.
  Conditions:
  Ambient Temperature 21.5oC
  Relative Humidity 62.3%
  CL-200 Temperature Controller:
  Set Temperature SC-20 0.0oC
  QE-1HV Plate Set Temperature 0.0oC
  Flow Rate 2 ml/min.
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  6. The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active
    Xiao R, Tian J, Tang J, Zhu MX
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  7. Highly Ca2+-selective TRPM channels regulate IP3-dependent oscillatory Ca2+ signaling in the C. elegans intestine
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  8. Divergent Biophysical Defects Caused by Mutant Sodium Channels in Dilated Cardiomyopathy With Arrhythmia
    Nguyen TP, Wang DW, Rhodes TH, George AL Jr
    Circ Res. 2008 Feb 15;102(3):364-71
  9. A Role of the Transient Receptor Potential Domain of Vanilloid Receptor I in Channel Gating
    García-Sanz N, Valente P, Gomis A, Fernández-Carvajal A, Fernández-Ballester G, Viana F, Belmonte C, Ferrer-Montiel A
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  13. Subtype-Specific GABA Transporter Antagonists Synergistically Modulate Phasic and Tonic GABAA Conductances in Rat Neocortex
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  14. High-Concentration Rapid Transients of Glutamate Mediate Neural-Glial Communication via Ectopic Release
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    J Biol Chem. 2005 Apr 22;280(16):15928-41
DOCUMENT DESCRIPTION
Integrated Components Brochure_06_7_11.pdfIntegrated Components for Live Cell Imaging Brochure
SC-20 (060701).pdfIn-line Heater/Cooler (SC-20) Manual