IH-5 - Complete Isolated Langendorff and/or Working Heart Perfusion System for Large Rodents (Rat, Guinea Pig, Rabbit)

IH-5 - Complete Isolated Langendorff and/or Working Heart Perfusion System for Large Rodents (Rat, Guinea Pig, Rabbit)

The Isolated Heart Size 5, IH-5, apparatus permits the use of hearts of small animals (rodents) as well as larger animals like rabbits. The flow limitation is about 500 ml/min. The perfusate is oxygenated in a 6 liter water jacketed reservoir with multiple ports for recircualtion of the perfusate.

Item# Description U.S. List Price Quantity
73-9901 IH-5 - Isolated Heart System for Large Rodents (Rats, Guinea Pigs, Rabbits)
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• High perfusion pressure (up to 300 mmHg); easy and fast changes of the perfusion pressure (within seconds)
• Continuous measurement of heart mechanics (contractility, segment lengths), bioelectrical signals (ECG, MAP) and perfusate characteristics (pCO2, pO2, pH)
• The system can easily be modified to a working heart system, the special flow resistance and compliance chamber mimics closely the in-vivo afterload
• Multiple monophasic action potentials (MAP) and simultaneous multi-lead ECG recording from Isolated Perfused Rabbit heart
• Extended system for hemodynamic and electro-physiology studies
• Applications:
– Dispersion of ventricular repolarization
The Isolated Heart Size 5, IH-5, apparatus permits the use of hearts of small animals (rodents) as well as larger animals like rabbits. The flow limitation is about 500 ml/min. The perfusate is oxygenated in a 6 liter water jacketed reservoir with multiple ports for recircualtion of the perfusate.
The system can be used for work in any one of three methods. The basic system is the retrograde perfusion mode (Langendorff). By setting a defined threshold pressure at the flow resistance, the system works under constant pressure; by increasing the threshold pressure to a supermaximal pressure (300 mmHg) the system works under constant flow. A working heart system can be arranged by using the Left Atrium Cannulating Option. The complete system is mounted on a compact acrylic stand.
The system can also be used to simultaneously record all hemodynamic parameters as well as 8 MAP-potentials and a 12-lead ECG. For this purpose, the IH-5 unit is additionally equipped with a circular holder for 8 MAP-electrodes and with an ECG multi-electrode insert in the heart chamber.
Specifications73-9901
Package1
Product FamilyHugo Sachs Perfusion Systems