HSE-HA Stimulator CS for Isolated Cells

HSE-HA Stimulator CS for Isolated Cells

For the electrical stimulation of isolated cells, e.g. myocytes.

Item# Description U.S. List Price Quantity
73-2667 HSE-HA Stimulator CS for Isolated Cells, 115 VAC, 60 Hz
73-0485 HSE-HA Stimulator CS for Isolated Cells, 220 VAC, 50 Hz
Login for U.S. Pricing

• Easy to use
• Constant voltage mono-phasic, biphasic or alternating stimulation (> 1A)
• High output impulse current
• Backup memory for timing setting
• Specially adapted for isolated cell stimulation

The stimulator CS Type 223 is a new development of an electronic stimulator for the electrical stimulation of isolated cells, e.g. myocytes. Stimulating isolated cells needs a high impulse current to trigger a maximum of cells independent of the size, shape specially in cell culture medium having a low resistance. This is of importance in experiments where the threshold voltage of cell reaction has to be determined. To reduce electrochemistry effects such as polarization of the electrodes and double layer of gas bubbles biphasic stimulation with perfect symmetry is requested. To be able to activate an action potential by depolarizing the membrane and to avoid further influence of the stimuli on the cell reaction, short and powerful impulses are required.

Stimulation Mode and Timing are displayed on a LCD display and can easily be set in a step through mode using the ‘Menu’ button and the adjust knob. The last setting of the timing is stored in a backup memory and recalled automatically after switching on the instrument. The Stimulus Output Voltage is indicated on the built-in digital voltmeter and can be Adjusted on two potentiometers: “coarse” and “fine” with adjustment in the range of 0 to 45 V. The output is floating, not connected to earth (ungrounded). The output has a very low impedance (less than 1 Ohm). To avoid overheating of the output circuit a dynamic current limiter is built in. It limits the maximum output current relative to the Stimulation Width.

Specifications73-266773-0485
Delay Time(leading the stimuli): 2 to 50 msec (in 7 steps) 2, 5, 10, 20, 30, 40, 50 msec(leading the stimuli): 2 to 50 msec (in 7 steps) 2, 5, 10, 20, 30, 40, 50 msec
Dimension (H x W x D) English4.3 x 11.8 x 9.8 in4.3 x 11.8 x 9.8 in
Dimensions (H x W x D) Metric100 x 300 x 250 mm100 x 300 x 250 mm
Indicators - 11. LCD module (4 lines of 16 characters each) to indicate stimulus parameter settings (except amplitude)
2. Digital voltmeter (DVM) to indicate output voltage setting range selectable: 0 - 19.99 V <‐‐‐> 0 - 50.0 V
1. LCD module (4 lines of 16 characters each) to indicate stimulus parameter settings (except amplitude)
2. Digital voltmeter (DVM) to indicate output voltage setting range selectable: 0 - 19.99 V <‐‐‐> 0 - 50.0 V
Indicators - 23. LED for stimulus pulse
4. Beep (with each stimulus pulse), can be switched off
5. 2 LEDs for polarity of next stimulus: + or -
3. LED for stimulus pulse
4. Beep (with each stimulus pulse), can be switched off
5. 2 LEDs for polarity of next stimulus: + or -
Stimulation Mode 1SINGLE/STRT single stimulus triggered by START switch or by remote contactSINGLE/STRT single stimulus triggered by START switch or by remote contact
Stimulation Mode 2REPEAT/STRT repeating stimulus triggered by START switch or by remote contactREPEAT/STRT repeating stimulus triggered by START switch or by remote contact
Stimulation Mode 3TRIGGER pulse (TTL, negative-going edge) starts delay circuit; START switch must be in OFF positionTRIGGER pulse (TTL, negative-going edge) starts delay circuit; START switch must be in OFF position
Stimulus Output1. Output voltage 0 to 50 V; Pulse Current up to 1 A at max. pulse width (10 msec)
2. Monophasic, Biphasic, Alternated
3. Output circuit floating, not connected to earth (ungrounded)
1. Output voltage 0 to 50 V; Pulse Current up to 1 A at max. pulse width (10 msec)
2. Monophasic, Biphasic, Alternated
3. Output circuit floating, not connected to earth (ungrounded)
Timing: Stimulation Frequency0.05 to 100 Hz (in 29 steps) 0.05, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100 Hz0.05 to 100 Hz (in 29 steps) 0.05, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100 Hz
Timing: Stimulus Width10 µsec to 10 msec (in 28 steps) 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 200, 300, 400, 500, 600, 700, 800, 900 µsec10 µsec to 10 msec (in 28 steps) 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 200, 300, 400, 500, 600, 700, 800, 900 µsec
Trigger InputBNC socket, input signal starts time delay, TTL level, negative active edgeBNC socket, input signal starts time delay, TTL level, negative active edge
Trigger OutputBNC socket, signal: delay time, open collector output (2 kΩ to +5V)BNC socket, signal: delay time, open collector output (2 kΩ to +5V)
Weight (English)7.7 lbs7.7 lbs
Weight (Metric)3.5 kg3.5 kg