Graz Tissue Bath System

Graz Tissue Bath System

The Graz Organ Bath can be used for many standard pharmacological experiments. This apparatus was developed for experiments on small isolated vascular rings (1 to 2 mm dia.) with special attention to a low incubation volume of the medium. The smallest tissue vessel available has a volume of 2 ml. The muscle contractions produced in these experiments can be measured either as forces (isometrically) or as displacements (isotonically).

 

To ensure that your system is properly configured to meet your application needs, please contact Technical Services at 800-547-6766 or via email before placing an order. We would also be happy to answer questions you might have about any of our tissue and organ bath systems.

Item# Description U.S. List Price Quantity
73-2369 BASIC UNIT FOR 4-POSITION ORGAN BATH, MODEL GRAZ, TYPE 846
73-9917 Graz Vertical Tissue Bath System
73-0559 MOUNTING MATERIAL FOR TISSUE VESSEL AND TISSUE HOLDER
73-0560 HOLDER FOR 10 OR 20 ML GRAZ GLASS TISSUE BATH
73-2271 GLASS TISSUE BATH, 10 ML, JACKETED, FOR GRAZ ORGAN BATH
73-2276 GLASS TISSUE BATH, 20 ML, JACKETED, FOR GRAZ ORGAN BATH
73-0561 HOLDER FOR 2 OR 5 ML GRAZ GLASS TISSUE BATH
73-2273 GLASS TISSUE BATH, 2 ML, JACKETED, FOR GRAZ ORGAN BATH
73-2275 GLASS TISSUE BATH 5 ML, JACKETED, FOR GRAZ ORGAN BATH
73-3531 CORE TISSUE HOLDER WITHOUT ELECTRICAL STIMULATION FOR GRAZ BATH
73-3533 CORE TISSUE HOLDER WITH FIELD STIMULATION ELECTRODES, FOR 10 OR 20 ML GRAZ TISSUE BATH
73-3532 CORE TISSUE HOLDER WITH FIELD STIMULATION ELECTRODES, FOR 2 OR 5 ML GRAZ TISSUE BATH
73-3535 SUPPORT SET FOR RINGS 0.5MM WIRE TO CORE TISSUE HOLDER FOR GRAZ BATH (LARGE VERSION MAX RING LENGTH 11MM)
73-3537 SUPPORT SET FOR RINGS 0.3MM WIRE TO CORE TISSUE HOLDER FOR GRAZ BATH (MAX RING LENGTH 6MM)
73-3534 SUPPORT SET FOR STRIPS TO CORE TISSUE HOLDER FOR GRAZ BATH
73-2117 GAS DISTRIBUTION BLOCK FOR BUBBLING FOR GRAZ BATH AND OTHERS
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  • Designed for vascular rings but suitable for most standard pharmacological experiments
  • Permits experiments both on smooth muscle, cardiac (atria), or skeletal muscles preparations
  • Clear, 4-channel arrangement
  • Rigid construction
  • Contractions can be measured isometrically or isotonically
  • Interchangeable tissue vessels: 2, 5, 10 or 20 ml
  • Experiments with minimum test substance quantities are possible using small tissue vessels
  • Adaptable to different tissue preparations by suitable form of tissue supports
  • Tissue holders with integral field stimulating electrode available
  • Simple to operate, easy to clean
The Graz Organ Bath can be used for many standard pharmacological experiments. This apparatus was developed for experiments on small isolated vascular rings (1 to 2 mm dia.) with special attention to a low incubation volume of the medium. The smallest tissue vessel available has a volume of 2 ml. The muscle contractions produced in these experiments can be measured either as forces (isometrically) or as displacements (isotonically).

The organ bath is also available in variable versions. Larger tissue vessels of 5, 10 or 20 ml are available for larger vessels and other muscle preparations. These baths can also be used for experiments on papillary muscle or isolated atria (e.g. guinea-pig), with provision for electrical stimulation.

The F-30 isometric transducer that we recommend can easily be replaced by different transducers without any modification of the apparatus.
The main consideration in designing the bath has been a simple and clear arrangement, without neglecting the necessary stability. A rigid construction is an essential requirement for measuring small contraction forces. A rigid Plexiglas baseplate carriers 4 vertical rods on which the individual components are mounted. Tissue vessels and suitable holders are available in 4 different sizes. The perfusion solution is aerated by glass frits fused into the vessel bottom. A needle valves is provided for each tissue vessel to permit accurate adjustment of the gas flow.
Specifications73-9917
Package1
Product FamilyHugo Sachs Tissue Baths