Coleman Superfusion Bath System

Coleman Superfusion Bath System

Suitable for a variety of applications involving the study of contraction and relaxation of smooth muscle preparations, the effect of drugs that interfere with these actions, as well as those that interfere with autonomic neurotransmission.

To ensure that your system is properly configured to meet your application needs, please contact Technical Services at 800-547-6766 or via email before placing an order. We would also be happy to answer questions you might have about any of our tissue and organ bath systems.

Item# Description U.S. List Price Quantity
73-2221 BASIC UNIT FOR SUPERFUSION BATH ACCORDING TO COLEMAN (4-POSITION) TYPE 840
73-2222 SUPERFUSION BATH ACCORDING TO COLEMAN
73-2917 Dual Heat Exchanger for Coleman Superfusion Bath
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The Coleman Superfusion Tissue Bath System is suitable for applications involving the study of contraction and relaxation of smooth muscle preparations, the effect of drugs that interfere with these actions, and those that interfere with autonomic neurotransmission.

Features & Benefits

  • Suitable for virtually any tissue sample
  • Compact, allows the study of up to four tissue preparations in parallel
  • Rapid removal of potentially toxic metabolites
  • Obviates the necessity of repeated washing procedures
  • Simple reclamation of perfusate for recirculation or collection

Applications

  • Evaluation of the potency of labile substances
  • Determining the rates of onset and offset of drug action
  • Evaluation of spasmogenic and spasmolitic agents



Modes of Operation

 

Flow through mode: Each tissue is superfused individually with fresh solution or solution containing the test compound. The outcoming solution is collected and goes to waste or is stored for later bioassay analysis.

Recirculating mode: Each tissue is superfused individually. The outcoming solution after superfusion is collected and used for superfusing again in the same tissue.

Cascade mode: The first tissue is superfused with fresh solution and all the subsequent tissues are superfused with the outcoming solution of the preceding chamber.


Included items: Stand (capacity 8 chambers), frame, Plexiglas chambers (4), tisue holder, dual heat exchanger, rod for mounting transducer

Additional equipment required: Peristaltic pump, force transducer withVernier control, bridge amplifier for the force transducer, Data acquisitionACAD, electrical stimulator, thermocirculator if heat exchangers are used.

Specifications