BASIC IH-SR (COMMON SYSTEM) FOR ISOLATED SMALL RODENT HEART, 230 VAC 73-4343

BASIC IH-SR (COMMON SYSTEM) FOR  ISOLATED SMALL RODENT HEART, 230  VAC 73-4343

TThe  IH-SR Langendorff serves as the starting point for all isolated heart  experiments. Advanced engineering provides ease-of-use and exceptional  stability of measurements while maintaining the flexibility to upgrade  to more advanced capabilities.

The system includes virtually everything you need to accomplish the basic Langendorff experiment: - Basic Unit IH-SR for Isolated Small Rodent Hearts - Thermo Circulator - Analog Roller Pump Reglo - Perfusion pressure measurement (Pressure Transducer and TAM-D Transducer Amplifier Module) - PLUGSYS Basic System Case 603 - Measurement system for isovolumetric LVP measurement using balloon (Pressure Transducer, Holder for Pressure Transducer and TAM-A Transducer Amplifier Module does not include balloon)

A full working system requires in addition:
73-4019 ADDITIONS TO IH-SR CORE SYSTEM FOR MOUSE HEARTS

For Langendorff only:
73-3996 SCP-2 PLUGSYS SERVO CONTROLLER for PERFUSION TYPE 712
Prepared for working Heart addition lateron:
73-4346 PERFUSION PRESSURE CONTROL WITH STARTLING RESISTOR
and
73-4021 DIRECT FLOW MEASUREMENT FOR MOUSE HEARTS

addition we recommend a selection of DAQ-System 73-xxxxx or 77-xxxx

 

Item# Description U.S. List Price Quantity
00-0739 BASIC UNIT IH-SRL FOR ISOLATED SMALL RODENT HEART TYPE 844/4 (L), 00-0739
73-0125 THERMOSTATIC CIRCULATOR E 103, BATH VOLUME 3 L, 230 V/50 Hz
73-2448 ISM 829/230V ROLLER PUMP REGLO ANALOGUE, 2 CHANNELS, 0.005 - 49.4 ML/MIN
73-0045 PLUGSYS Case, Type 603
73-1793 Transducer Amplifier Module (TAM-D)
73-0065 Transducer Amplifier Module (TAM-A)
73-3862 APT300 Pressure Transducer for PLUGSYS Module
73-3869 Holder for APT300 Transducer, 8mm Rod, Length 75mm
73-0566 Plexiglass Block Clamp - for mounting 73-4337 Bar onto Lab Stand
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Includes: Basic Unit IH-SR for Isolated Small Rodent Hearts, Thermo Circulator, Analog Roller Pump Reglo, Perfusion pressure measurement (Pressure Transducer and TAM-D Transducer Amplifier Module), PLUGSYS Basic System Case 603 Measurement system for isovolumetric LVP measurement using balloon (Pressure Transducer, Holder for Pressure Transducer and TAM-A Transducer Amplifier Module does not include balloon) Measured Signals: Perfusion Pressure, isovolumetric LVP measurement with balloon. 00-0739 BASIC UNIT IH-SRL FOR ISOLATED SMALL RODENT HEART TYPE 844/4 (L), 00-0739 73-0125 THERMOSTATIC CIRCULATOR E 103, BATH VOLUME 3 L, 230 V/50 Hz 73-2448 ISM 829/230V ROLLER PUMP REGLO ANALOGUE, 2 CHANNELS, 0.005 - 49.4 ML/MIN 73-0045 PLUGSYS Case, Type 603 73-1793 TRANSDUCER AMPLIFIER MODULE (TAM-D) 73-0065 TRANSDUCER AMPLIFIER MODULE (TAM-A) 73-3862 APT300 Pressure Transducer for PLUGSYS Module 73-3869 Holder for APT300 Transducer, 8mm Rod, Length 75mm 73-0566 Perspex Block Clamp to mount transducer onto rod (up to 9mm OD) For a working unit, the core system requires the addition of a selection of one of the perfusion pressure controller systems (SCP or STARLING-IHSR) and one of the options IHSR-MOUSE or IHSR-RAT/GP. The working heart ready configuration also requires the species-appropriate direct flow measurement option.
Specifications73-244873-004573-179373-006573-386273-3869
Mounting Rod Length MetricSpeed Control 0 - 5 V or 0 - 10 V and 0 - 20 mA respectivelyLine Cable, Spare Fuses, Screw driver for fitting Function Modules, Document Folder for Operating Instructions of Function Modules, 3 x BNC-BNC Output linesTAM-A LED bar graph 20 LEDs (+13/-7) for visual check on the signal sensitivity approx. 1V/LED TAM-D 3 1/2-digit LED displayTAM-A LED bar graph 20 LEDs (+13/-7) for visual check on the signal sensitivity approx. 1V/LED TAM-D 3 1/2-digit LED displayCE75 mm
Mounting Rod OD Metric1.0 bar (14.5 PSI)5.2 x 19 x 17.1 inThrough 10-turn trimmer coarse adjustment and electronic autozero by push button (LED for error if autozero is not possible)Through 10-turn trimmer coarse adjustment and electronic autozero by push button (LED for error if autozero is not possible)3 m8 mm

• Compact design, optimized individually for: mouse, rat or guinea pig
• Constant pressure or constant flow perfusion in one unit, easily switch between the two modes
• Compact, doesn’t require wall-installed high water columns, suitable for hearts from hypertensive rats (perfusion pressures up to 300 mmHg are possible)
• Unique integrated small volume Aortic Block with built-in bubble trap and windkessel
• Large fully-heated heart chamber


- Natural physiological environment for the isolated heart
- Hearts are kept alive for hours in a very stable physiologic environment
- Easy-to-use with smooth open and closed operation
- All electrodes, catheters and probes are fully enclosed for easy access and to maintain physiological conditions while performing the experiments.


• Unique cannula design


- Cannula resistance is optimized according to Hagen-Poiseuilles physical law
- Different cannula sizes available, all metal, no fragile glass cannulae


• Proprietary mini holders allow easy and stress-free positioning of electrodes, catheters and probes

 


MEASURED SIGNALS AND CALCULATED PARAMETERS ON THE IH-SR BASIC SYSTEM:
The following signals are recorded as raw data:


• Isovolumetric Left Ventricular Pressure (Balloon Method)
• Aortic (Perfusion) Pressure
• Coronary Flow*

 

The following parameters are calculated from the raw data (using DAQ system):


• dLVP/dt, dLVP/dt Max, dLVP/dt Min, Contractility Index
• Systolic and Diastolic LVP
• Heart Rate
• Mean Perfusion Pressure
• Mean Perfusion Flow*
• Coronary Resistance*

 

* This Parameter is based on Indirect Flow Measurement with Option IHSR-SCP or Direct Flow Measurement with IHSR-STARLING and IHSR-DIRECT added to the core system