BASIC IH-SR (COMMON SYSTEM) FOR ISOLATED SMALL RODENT HEART, 115 VAC 73-4344

BASIC IH-SR (COMMON SYSTEM) FOR  ISOLATED SMALL RODENT HEART, 115  VAC 73-4344

A full working system requires in addition:

73-4019 ADDITIONS TO IH-SR CORE SYSTEM FOR MOUSE HEARTS

For Langendorff only:
73-3996 SCP-2 PLUGSYS SERVO CONTROLLER for PERFUSION TYPE 712

Prepared for working Heart addition lateron:
73-4346 PERFUSION PRESSURE CONTROL WITH STARTLING RESISTOR

and
73-4021 DIRECT FLOW MEASUREMENT FOR MOUSE HEARTS

In addition we recommend a selection of DAQ-System 73-4039 or 77-0242

Item# Description U.S. List Price Quantity
00-0739 BASIC UNIT IH-SRL FOR ISOLATED SMALL RODENT HEART TYPE 844/4 (L), 00-0739
73-2802 THERMOSTATIC CIRCULATOR E 103, BATH VOLUME 3 L, 115 V/60 Hz
73-2952 ISM 829/115V ROLLER PUMP REGLO ANALOGUE, 2 CHANNELS, 0.005 - 49.4 ML/MIN
73-0045 PLUGSYS Case, Type 603
73-3862 APT300 Pressure Transducer for PLUGSYS Module
73-1793 Transducer Amplifier Module (TAM-D)
73-3869 Holder for APT300 Transducer, 8 mm Rod, Length 75 mm
73-0566 Plexiglass Block Clamp - for mounting 73-4337 Bar onto Lab Stand
73-0065 Transducer Amplifier Module (TAM-A)
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Includes: Basic Unit IH-SR for Isolated Small Rodent Hearts, Thermo Circulator, Analog Roller Pump Reglo, Perfusion pressure measurement (Pressure Transducer and TAM-D Transducer Amplifier Module), PLUGSYS Basic System Case 603 Measurement system for isovolumetric LVP measurement using balloon (Pressure Transducer, Holder for Pressure Transducer and TAM-A Transducer Amplifier Module does not include balloon) Measured Signals: Perfusion Pressure, isovolumetric LVP measurement with ballon. For a working unit, the core system requires the addition of a selection of one of the perfusion pressure controller systems (SCP or STARLING-IHSR) and one of the options IHSR-MOUSE or IHSR-RAT/GP. The working heart ready configuration also requires the species-appropriate direct flow measurement option.
Specifications73-295273-004573-179373-0065
Analog IndicationSpeed Control 0 - 5 V or 0 - 10 V and 0 - 20 mA respectivelyLine Cable, Spare Fuses, Screw driver for fitting Function Modules, Document Folder for Operating Instructions of Function Modules, 3 x BNC-BNC Output linesTAM-A LED bar graph 20 LEDs (+13/-7) for visual check on the signal sensitivity approx. 1V/LED TAM-D 3 1/2-digit LED displayTAM-A LED bar graph 20 LEDs (+13/-7) for visual check on the signal sensitivity approx. 1V/LED TAM-D 3 1/2-digit LED display
Bridge Balance1.0 bar (14.5 PSI)5.2 x 19 x 17.1 inThrough 10-turn trimmer coarse adjustment and electronic autozero by push button (LED for error if autozero is not possible)Through 10-turn trimmer coarse adjustment and electronic autozero by push button (LED for error if autozero is not possible)
Bridge Supply Voltage5.6 x 3.9 x 7 in132 x 483 x 435 mm+5V / 50 mA max.+5V / 50 mA max.
Electrical Calibration143 x 100 x 178 mmMetallic housing, gray plastic coated, Universal 19 inch case with pivoting feet, prepared for rack mountingSelectable by switch on front panel:
a) 0 V output signal with switch in position '0'
b) Positive or negative calibration output voltage adjustable with 10-turn trimmer if switch is in position 'CAL'
Selectable by switch on front panel:
a) 0 V output signal with switch in position '0'
b) Positive or negative calibration output voltage adjustable with 10-turn trimmer if switch is in position 'CAL'
GainRotation direction, Start/Stop20 slot units max.Selectable ranges by internal Jumper: 0.2 to 10, 0.4 to 20, 1 to 50, 2 to 100, 4 to 200, 10 to 500, 20 to 1000, 100 to 5000, 200 to 10000. Fine Adjustment Through 10-Turn TrimmerSelectable ranges by internal Jumper: 0.2 to 10, 0.4 to 20, 1 to 50, 2 to 100, 4 to 200, 10 to 500, 20 to 1000, 100 to 5000, 200 to 10000. Fine Adjustment Through 10-Turn Trimmer
Output Low-Pass Filter115 V / 50 Hz or 230 V / 50 Hz100 to 240 VAC, 50/60 Hz, built-in line filter, 100 W max. consumptiona) Selectable by switch on front panel for pulsatile output signal: 1, 100, 300 Hz
b) Selectable by internal jumper for mean output signal: 0.1, 0.3 Hz
a) Selectable by switch on front panel for pulsatile output signal: 1, 100, 300 Hz
b) Selectable by internal jumper for mean output signal: 0.1, 0.3 Hz
PLUGSYS Width*57 ml/min3-pin IEC mains with fuse and mains switch on back of housing2 slot units2 slot units
Power Supply0.002 ml/min14.3 lbs+5V through connector from PLUGSYS bus system+5V through connector from PLUGSYS bus system
Signal Output26.5 kga) On front panel through BNC socket a) On front panel through BNC socket
Transducer Input86-pin socket with screw lock (binder, Amphenol Tuchel) Differential input circuit, imput impedance 1010?6-pin socket with screw lock (binder, Amphenol Tuchel) Differential input circuit, imput impedance 1010?
20 W
IP 30
yes
MS-2/8-160
1.6 to 160 rpm
Adjustable in 1% steps (0-99%)
3 to 99%, resolution 1%, 2 digit potentiometer
7-8 m
MS/CA Click 'n' Go - Cassettes are included
115 VAC
2.0 kg
4.4 lbs

• Compact design, optimized individually for: mouse, rat or guinea pig
• Constant pressure or constant flow perfusion in one unit, easily switch between the two modes
• Compact, doesn’t require wall-installed high water columns, suitable for hearts from hypertensive rats (perfusion pressures up to 300 mmHg are possible)
• Unique integrated small volume Aortic Block with built-in bubble trap and windkessel
• Large fully-heated heart chamber


- Natural physiological environment for the isolated heart
- Hearts are kept alive for hours in a very stable physiologic environment
- Easy-to-use with smooth open and closed operation
- All electrodes, catheters and probes are fully enclosed for easy access and to maintain physiological conditions while performing the experiments.


• Unique cannula design


- Cannula resistance is optimized according to Hagen-Poiseuilles physical law
- Different cannula sizes available, all metal, no fragile glass cannulae


• Proprietary mini holders allow easy and stress-free positioning of electrodes, catheters and probes

 


MEASURED SIGNALS AND CALCULATED PARAMETERS ON THE IH-SR BASIC SYSTEM:
The following signals are recorded as raw data:


• Isovolumetric Left Ventricular Pressure (Balloon Method)
• Aortic (Perfusion) Pressure
• Coronary Flow*

 

The following parameters are calculated from the raw data (using DAQ system):


• dLVP/dt, dLVP/dt Max, dLVP/dt Min, Contractility Index
• Systolic and Diastolic LVP
• Heart Rate
• Mean Perfusion Pressure
• Mean Perfusion Flow*
• Coronary Resistance*

 

* This Parameter is based on Indirect Flow Measurement with Option IHSR-SCP or Direct Flow Measurement with IHSR-STARLING and IHSR-DIRECT added to the core system